Small-start Type: Full-scale R&D Projects
Development of digital twin by integrating multi-layered biomedical information
| Prioritized Theme | Human centric digital twins services |
|---|---|
| R&D Period | 2024.04- (Feasibility Study: 2021.10-2024.03) |
| Grant Number | JPMJMI24H2 |
| Project Summary | Summary (PDF:434KB) |
Summary:
Disease prevention is one of the key issues to promote human health and to maintain socialvitality.
The purpose of this project is to develop a new digital twin technology for predicting personalizedrisks of diseases and for simulating future health conditions of individuals by incorporating information of DNA polymorphisms and omics into that of long-term health checkup records.
In the feasibility study R&D project, we focused onunique health checkup systems of Japanese companies, constructed a cohort with DNA polymorphisminformation of 60,000 people, and successfullycalculated and verified the disease risks (polygenic riskscore:PRS) for prevention of several common diseases.
In the full-scale R&D project, its scope will beexpanded to 38 diseases and 200,000 people.
Moreover, by utilizing cutting-edge information science,more advanced and novel digital twin technology thatincludes not only genomic information but also omicsand biophysical information will be developed andpersonalized approaches to disease prevention will begenerated.
R&D Team
The University of Tokyo, Institute of Science Tokyo, National Cancer Center,
NTT Precision Medicine Corporation
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