Researchers
Motoaki Sano – Treatment and prevention of heart failure by immunomodulation
Researcher
- Motoaki Sano
- Associate Professor, Departmen of Cardiology, Keio University School fo Medicine
Research Theme
Treatment and prevention of heart failure by immunomodulation
Heart failure is a phenotype that marks the final common pathway in a diversity of specific cardiovascular disease and is the main cause of death in our country. Dyspnea is a frequent limiting symptom and reduces the quality of life of heart failure patients. Neurohormonal blockade and the use of loop diuretics improve prognosis and help relieve dyspnea to a certain extent, but is far from satisfactory. We evaluate the impact of therapeutic intervention aimed at modulating the immune response in mouse models of heart failure due to myocardial infarction.