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Hiroto Shoji |
Assistant Professor, Department of Medicine,
Kyoto Prefectural University of Medicine |
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The Analysis of Three-dimensional Specific Morphology in Biology |
The hepatic function partly depends on the sinusoidal capillary network in hepatic lobule, and understanding how three-dimensional (3D) sinusoidal capillary networks form is essential objective. In this research, we focus on 3D specific sinusoidal capillary network patterns in hepatic lobule. We derive the feature quantity of 3D sinusoidal capillary patterns based on image analysis on spatial statics. Moreover, we provide a mathematical model for cell-to-cell interaction in order to identify mechanical interactions in complexity of formation of 3D patterns. On the basis of the spatial statics of 3D image in hepatic lovule and theoretical insights, we construct the analytical concept on 3D self-organized morphology in biological systems. |
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