Fundamental development of multi-dimensional exhaustive quantity observation technology for iPS research field
Tomonobu M Watanabe Assistant professor, Immunology Frontier Research Center
The induced pluripotent stem cell (iPS cell) is expected to considerably contribute biology and medical field as a stem cell that can evade bioethics and rejection problems. The aim of this project is to reveal the reprogramming and the induction of differentiation of the iPS cell as a complex system based on a state transition on gene expressions, the protein behaviors and the interactions of intercellular network. To achieve this, this project is going to develop “quantity measurement technology of the localization, the function, and the movement” of the proteins and the cells during the reprogramming/differentiation process of the iPS cell.