Establishment and analysis of naive state human iPS/ES cells
Yasuhiro Takashima Research Associate, Wellcome Trust Centre for Stem Cell Research
University of Cambridge, UK
It is widely believed that human pluripotent stem cells will be a useful tool for clinical application of regenerative medicine. However, currently available human pluripotent stem cells are more heterogeneous than mouse naive state pluripotent stem cells. It will be a great advantage to establish human ground state cells equivalent to the homogenous populations of mouse pluripotent stem cells as the difference between cell lines is much less varied. This will allow for more precise and consistent human ES cell differentiation protocols.