The development method of using linkage analysis and iPS/ES technology
Hidetoshi Date Research Associate, The University of Tokyo Hospital, Department of Neurology
The University of Tokyo
Genetic linkage, classical powerful method, describes the tendency of certain loci or alleles to be inherited together. But, this powerful method is dependent on the number of disease-pedigrees, completely. My goal of this project is development method that determine the causative gene using RNA-seq information from the patient’s iPS cell of a single pedigree.