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3-years research type: Taro Muto Yasuji Kitabatake Yasuhiro Takashima Hidetoshi Date
Akitsu Hotta Kazuhiro Yagita Tomonobu M Watanabe  
5-years research type: Keiko Shimojima Jun K. Takeuchi    

Taro Muto

Establishment of experimental human genetics

photo Taro Muto
Assistant Professor, Institute of Health Biosciences

The University of Tokushima

Forward genetics in man is beneficial, in terms of (i) diagnoses and treatments of genetic diseases and (ii) discoveries of gene functions. However, experimental mating is not available in human genetics. In order to escape this dilemma, I try to establish a novel experimental procedure to genetically identify human disease gene loci without mating the patients with others. Using this technique, one carrier of the genetic mutations would be enough to identify the disease gene loci, if the abnormality is reproducible using patients-derived cells.

 

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