Project Details

JST HOME SATREPS HOME ProjectsInfectious Diseases Control

Main content

Infectious Diseases Control

  • SDGs3
  • SDGs17
  • SDGs1
Principal Investigator (Affiliation) 日本 Prof.
TOKUNAGA Katsushi
(Graduate School of Medicine, The University of Tokyo)
タイ Dr.
Surakameth Mahasirimongkol
(Senior Physician, Department of Medical Sciences, Ministry of Public Health)
Research Institutions in Japan The University of Tokyo / RIKEN / Research Institute of Tuberculosis (JATA) / Fukujuji Hospital (JATA)
Research Institutions in Thailand Ministry of Public Health, Thailand / Mahidol University
Adoption fiscal year FY2014
Research Period 4 Years
ODA Recipient Country Kingdom of Thailand
General Description of the Research Project

Revealing genetic risks of tuberculosis and developing effective treatments for tuberculosis
 Tuberculosis is an infectious disease and its burden for global health is well-known as HIV and malaria. Thailand is one of 22 high burden countries of tuberculosis, and effective measures are required to control this disease urgently. Genome variation in both humans and TB bacteria may affect different phenotype and treatment. This large-scale study will analyze the variation of both host and pathogen genomes among TB patients, patients who suffered side effects from the medication, and individuals who have not developed TB, in order to reveal how genomic DNA variants are associated with the development of TB and the side effects of the drug treatment.

Tuberculosis control will be advanced in Thailand and world through the application of genomic information
 From the results of the genomic analysis, this project will identify genetic factors associated with tuberculosis and establish highly effective and less side-effect causative treatment method. The research finding will contribute to reduce TB patients and provide better quality of life to the patients globally.

Photo gallery
イメージ1

Collaborative activity with Thai researchers operating a next-generation sequencer

イメージ2

Site visit to collect clinical information for understanding the environment around tuberculosis patients

イメージ3

Ministry of Public Health, Thailand

Research Project Web site
Press Release
Reports -
Links

Project Map | Project List