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Basic Research Programs Establishment of basic technologies for controlling of cell functions based on metabolic regulation mechanism analysis

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Publications

| @1st, 2005@|@ ŸTo 2nd, 2006 @|@ŸTo 3rd, 2007


Mitsuhiro Yanagida (Investigator (Professor extraordinary), Kyoto University)

Molecular network that supports chromosome segregation metabolism

Fiscal Year 2006

Research Paper List
  • Histone H2B Mutations in Inner Region Affect Ubiquitination, Centromere Function, Silencing and Chromosome Segregation., Maruyama, T., Nakamura, T., Hayashi, T., and Yanagida, M., EMBO J., 25, 2420 - 2431 (07 Jun 2006) Article
  • Cdc48 is Required for the Stability of Cut1/separase in Mitotic Anaphase, Ikai, N., Yanagida, M., J.Structural Biol., 156,50-61, 2006
  • Fission Yeast MAP Kinase is Required for the Increased Securin-Separase Interaction that Rescues Separase Mutants Under Stress, Kawasaki, Y., Nagao, K., Nakamura, T., Yanagida, M., Cell Cycle, 5:16, 1831-1839, 2006
  • Cdc2 Phosphorylation of the Fission Yeast Dis1 Ensures Accurate Chromosome Segregation, Aoki, K., Nakaseko, Y.,inoshita, K., Goshima, G., Yanagida, M., Current Biology, 16, 1627-1635, 2006
  • Coordinated Requirements of Human Topo II and Cohesin for Metaphase Centromere Alignment under Mad2-dependent Spindle Checkpoint Surveillance, Toyoda, Y., and Yanagida, M., Mol. Biol. Cell 17: 2287-2302; 2006
  • The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase, Kumada, K., Yao, R., Kawaguchi, T., Karasawa, M., Hoshikawa, Y., Ichikawa, K., Sugitani, Y., Imoto, I., Inazawa, J., Sugawara, M., Yanagida. M., and Noda, T., The Journal of Cell Biology, Volume 172, Number 6, 835-846, 2006
  • Priming of Centromere for CENP-A Recuruitment by Human hMis 18ƒΏ, hMis18ƒΐ, and M18BP1, Fujita, Y., Hayashi, T, Kiyomitsu, T., Toyoda, Y., Kokubu, A., Obuse, C., Yanagida, M., Developmental Cell 12, 17-30, January 2007
  • Ribonuclease Activity of Dis3 is Required for Mitotic Progression and Provides a Possible Link between heterochromatin and Kinetochore Function, Murakami, H., Goto, D., Toda, T., Chen, E., Grewal, S., Martienssen, R., Yanagida, M., PLoS ONE v.2(3)e317, March 2007,

Fiscal Year 2007

Research Paper List
  • Priming of Centromere for CENP-A Recuruitment by Human hMis 18ƒΏ, hMis18ƒΐ, and M18BP1, Fujita, Y., Hayashi, T, Kiyomitsu, T., Toyoda, Y., Kokubu, A., Obuse, C., Yanagida, M., Developmental Cell 12, 17-30, January 2007
  • Two-step, extensive alterations in the transcriptome from G0 arrest to cell division in Schizosaccharomyces pombe., Shimanuki M, Chung SY, Chikashige Y, Kawasaki Y, Uehara L, Tsutsumi C, Hatanaka M, Hiraoka Y, Nagao K, Yanagida M., Genes Cells. 2007 May;12(5):677-92.
  • Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1., Kiyomitsu T, Obuse C, Yanagida M., Developmental Cell 13(5):663-76, Nov.2007
  • Cut1/separase-dependent roles of multiple phosphorylation of fission yeast cohesin subunit Rad21 in post-replicative damage repair and mitosis., Adachi Y, Kokubu A, Ebe M, Nagao K, Yanagida M., Cell Cycle. 2007 Dec 29;7(6)
  • Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits., Hayashi T, Hatanaka M, Nagao K, Nakaseko Y, Kanoh J, Kokubu A, Ebe M, Yanagida M, Genes Cells. 2007 Dec;12(12):1357-70.
  • Tel2: a common partner of PIK-related kinases and a link between DNA checkpoint and nutritional response?, Kanoh J, Yanagida M., Genes Cells. 2007 Dec;12(12):1301-4. Review.
  • Dissection of the essential steps for condensin accumulation at kinetochores and rDNAs during fission yeast mitosis, Nakazawa N, Nakamura T, Kokubu A, Ebe M, Nagao K, Yanagida M. J Cell Biol. 2008 Mar 24;180(6):1115-31.
  • Diminishing HDACs by drugs or mutations promotes normal or abnormal sister chromatid separation by affecting APC/C and adherin, Kimata Y, Matsuyama A, Nagao K, Furuya K, Obuse C, Yoshida M, Yanagida M.. J Cell Sci. 2008 Apr 1;121(Pt 7):1107-18.

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