| @1st,2005@|@ To 2nd,2006 @|@To 3rd, 2007
Minoru Yoshida (Chief Scientist, Riken)
Global analysis of dynamics and network of protein modifications
Fiscal Year 2006
Research Paper List
- Iwabata H., Yoshida M., and Komatsu Y. Proteomic analysis of organ-specific post-translational lysine-acetylation and - methylation in mice by use of anti-acetyllysine and -methyllysine mouse monoclonal antibodies. Proteomics 5: 4653-4664, 2005
- Shinji C., Maeda S., Imai K., Yoshida M., Hashimoto Y., and Miyachi H. Design, synthesis, and evaluation of cyclic amide/imide-bearing hydroxamic acid derivatives as class-selective histone deacetylase (HDAC) inhibitors. Bioorg. Med. Chem. 14: 7625-7651, 2006
- Suzuki T., Kouketsu A., Itoh Y., Hisakawa S., Maeda S., Yoshida M., Nakagawa H., and Miyata N. Highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate. J. Med. Chem. 49(16): 4809-4812, 2006.
- Matsuyama A., Arai R., Yashiroda, Y., Shirai, A., Kamata, A., Sekido, S., Kobayashi, Y., Hashimoto, A., Hamamoto, M., Hiraoka, Y., Horinouchi, S., and Yoshida, M. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyses pombe. Nat. Biotechnol. 24(7): 841-847, 2006
- Shimazu T., Komatsu Y., Nakayama K. I., Fukazawa H., Horinouchi S., and Yoshida M. Regulation of SV40 large T-antigen stability by reversible acetylation. Oncogene 25: 7391-7400, 2006
- Shimazu T., Horinouchi S., and Yoshida M. Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing. J. Biol. Chem. 282(7): 4470-4487, 2007
Fiscal Year 2007
Research Paper List
- Hoshino, H., Nishino, T. G., Tashiro, S., Miyazaki, M., Ohmiya, Y., Igarashi, K., Horinouchi, S., and Yoshida, M. Corepressor SMRT and class II histone deacetylases promote Bach2 nuclear retention and formation of nuclear foci that are responsible for local transcriptional repression. J. Biochem. (Tokyo), 141: 719-727, 2007 May.
- Masuda A, Baba T, Dohmae N, Yamamura M, Wada H, Ushida K. Mucin (qniumucin), a glycoprotein from jellyfish, and determination of its main chain structure. J. Nat. Prod., 70: 1089-92, 2007 Jul.
- Manya H, Suzuki T, Akasaka-Manya K, Ishida HK, Mizuno M, Suzuki Y, Inazu T, Dohmae N, Endo T. Regulation of mammalian protein O-mannosylation: Preferential amino acid sequence for O-mannose modification. J. Biol. Chem., 282(28): 20200-6, 2007 Jul.
- Kaida, D., Motoyoshi, H., Tashiro, E., Nojima, T., Hagiwara, M., Ishigami, K., Watanabe, H., Kitahara, T., Yoshida, T., Nakajima, H., Tani, T., Horinouchi, S., and Yoshida, M. Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. Nature Chem. Biol., 3: 576-583, 2007 Sep.
- Lo, C.-W., Kaida, D., Nishimura, S., Matsuyama, A., Yashiroda, Y., Taoka, H., Ishigami, K., Watanabe, H., Nakajima, H., Tani, T., Horinouchi, S., and Yoshida, M. Inhibition of splicing and nuclear retention of pre-mRNA by spliceostatin A in fission yeast. Biochem. Biophys. Res. Commun., 364: 573-577, 2007 Dec.
- Kimata, Y., Matsuyama, A., Nagao, K., Furuya, K., Obuse, C., Yoshida, M., and Yanagida, M. Diminishing histone deacetylases by drugs or mutations promotes normal and abnormal sister chromatid separation via affecting APC/C and Mis4/Adherin. J. Cell Sci., 121: 1107-1118, 2008
- Shirai A, Matsuyama A, Yashiroda Y, Hashimoto A, Kawamura Y, Arai R, Komatsu Y, Horinouchi S, Yoshida M. Global analysis of gel mobility of proteins and its use in target identification. J. Biol. Chem., in press, 2008.
- Matsuyama A, Shirai A, Yoshida M. A series of promoters for constitutive expression of heterologous genes in fission yeast. Yeast, in press, 2008.
