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Basic Research Programs Establishment of basic technologies for controlling of cell functions based on metabolic regulation mechanism analysis

Toppage  >  Publications:Taguchi Team

Publications

|  1st, 2005 | ◆To 2nd, 2006  | ◆To 3rd, 2007


Ryo Taguchi (Professor, The University of Tokyo)

Construction of the fundamental system for lipid metabololics and its application

Fiscal Year 2005

Research Paper List
R.Taguchi Group
  • Toshiaki Houjou, Kotoko Yamatani, Masayoshi Imagawa, Takao Shimizu, Ryo Taguchi. A Shotgun tandem mass spectrometric analysis of phospholipids with normal-phase and/or reverse-phase liquid chromatography/electrospray ionization mss spectrometry.: Rapid Commun. Mass Spectrom., 19, 654-666 (2005)
  • Taguchi R, Houjou T, Nakanishi H, Yamazaki T, Ishida M, Imagawa M, Shimizu T. Focused lipidomics by tandem mass spectrometry.: J Chromatogr B Analyt Technol Biomed Life Sci. 25;823(1):26-36 (2005)
T.Yokomizo Group
  • Terawaki K, Yokomizo T, Nagase T, Toda A, Taniguchi M, Hashizume K, Yagi T, Shimizu T. Absence of leukotriene B4 receptor 1 confers resistance to airway hyperresponsiveness and Th2 type immune responses. J. Immunol. 175, 4217-4225, 2005
  • Yoshikawa K, Kita Y, Kishimoto K, Shimizu T. Profiling of eicosanoid production in the rat hippocampus during kainate-induced seizure: Dual-phase regulation and differential involvement of cox-1 and cox-2. J. Biol. Chem. 2006 (in press, DOI: 10.1074/jbc.M511089200)
T.Kobayashi Group
  • Satomi Tsuda, Shinichi Okudaira, Keiko Moriya-Ito, Masayuki Tanaka, Junken Aoki, Hiroyuki Arai, Kimiko Murakami-Murofushi, and Tetsuyuki Kobayashi (2006) Cyclic phosphatidic acid is produced by autotaxin in blood. J. Biol. Chem., in press.
E.Fukusaki Group
  • Fukusaki, E., K. Jumtee, T. Bamba, T. Yamaji, and A. Kobayashi, "Metabolic Fingerprinting and Profiling of Arabidopsis thaliana Leaf and its Cultured Cells T87 by GC/MS." Z Naturforsch [C]: in press.
  • Bamba, T., Fukusaki, E., Minakuchi, H., Nakazawa, Y., and Kobayashi, A.: Separation of polyprenol and dolichol by monolithic silica capillary column chromatography. J Lipid Res, 46, 2295-2298 (2005)

Fiscal Year 2006

Research Paper List
R.Taguchi Group
  • Nakanishi H, Shindou H, Hishikawa D, Harayama T, Ogasawara R, Suwabe A, Taguchi R, Shimizu T. Cloning and characterization of mouse lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1). Expression in alveolar type II cells and possible involvement in surfactant production. J. Biol. Chem. 21;281, 20140-20147, 2006
  • Oike H, Wakamori M, Mori Y, Nakanishi H, Taguchi R, Misaka T, Matsumoto I, and Abe K. Arachidonic acid can function as a signaling modulator by activating the TRPM5 cation channel in taste receptor cells. Biochim Biophys Acta. 1761, 1078-1084,2006
  • Shindou H, Hishikawa D, Nakanishi H, Harayama T, Ishii S, Taguchi R, Shimizu T. A single enzyme catalyzes both PAF production and membrane biogenesis of inflammatory cells: cloning and characterization of acetyl-CoA:lyso-PAF acetyltransferase. J Biol Chem. 9, 282, 6532-6539, 2007
K.Hanada Group
  • M. Kawano, K. Kumagai, M. Nishijima, and K. Hanada: Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT. J. Biol. Chem. 281, 30279-30288, 2006.
T.Yokomizo Group
  • Matsubara D, Niki T, Ishikawa S, Goto A, Ohara E, Yokomizo T, Heizmann C W, Aburatani H, Moriyama S, Moriyama H, Nishimura Y, Funata N, and Fukayama M. Differential Expression of S100A2 and S100A4 in Lung Adenocarcinomas: Clinicopathologic Significance, Relationship to p53, and Identification of Their Target Genes. Cancer Sci. 96, 844-857, 2005.
  • Doi, K., Okamoto, K., Negishi, K., Suzuki, Y., Nakao, A., Fujita, T., Toda, A., Yokomizo, T., Kita, Y., Kihara, Y., Ishii, S., Shimizu, T., and Noiri, E. Attenuation of folic acid-induced renal inflammatory injury in platelet-activating factor receptor-deficient mice. Am. J. Pathol. 168, 1413-1424, 2006
  • Hori, T., Ishijima, J., Yokomizo, T., Ago, H., Shimizu, T., Miyano, M. Crystal structure of anti-configuration of indomethacin and leukotriene B-4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complex reveals the structural basis of broad spectrum indomethacin efficacy. J. Biochem. 140, 457-466, 2006
  • Kunieda, K., Okuno, T., Terawaki, K., Miyano, M., Yokomizo, T., and Shimizu, T. Identification of the Intracellular Region of the Leukotriene B4 receptor type-1 that Specifically Involves in Gi-Activation. J. Biol. Chem. 282, 3998-4006, 2007
O.Kuge Group
  • Saito K, Nishijima M, Kuge O. Phosphatidylserine is involved in gene expression from Sindbis virus subgenomic promoter. Biochem Biophys Res Commun. 345, 878-85 (2006)
T.Kobayashi Group
  • Satomi Tsuda, Shinichi Okudaira, Keiko Moriya-Ito, Chie Shimamoto, Masayuki Tanaka, Junken Aoki, Hiroyuki Arai, Kimiko Murakami-Murofushi, and Tetsuyuki Kobayashi (2006) Cyclic phosphatidic acid is produced by autotaxin in blood. J. Biol. Chem. 281: 26081 - 26088.
  • Ayako Uchiyama, Mutsuko Mukai, Yuko Fujiwara, Susumu Kobayashi, Nobuyuki Kawai, Hiromu Murofushi, Masahiro Inoue, Shigenori Enoki, Yuichiro Tanaka, Tamotsu Niki, Tetsuyuki Kobayashi, Gabor Tigyi, and Kimiko Murakami-Murofushi (2006) Inhibition of Tumor Cell Invasion and Metastasis by Novel Carba-derivatives of Cyclic Phosphatidic Acid. Biochim. Biophys. Acta 1771: 103-112.
E.Fukusaki Group
  • Kim, J. K., E. Fukusaki, K. Harada, T. Bamba, A. Kobayashi. "Time course metabolic profiling in Arabidopsis thaliana cell cultures after salt stress treatment." J Exp Bot:;58(3),2007, 415-424.
  • Harada, K., E. Fukusaki, T. Bamba, F. Sato and A. Kobayashi "In vivo 15N-enrichment of metabolites in suspension cultured cells and its application to metabolomics." Biotechnol Prog 22(4): (2006) 1003-1011.
  • Ute, K., Yoshida, S., Kitayama, T., Bamba, T., Harada, K., Fukusaki, E., Kobayashi, A., Ishizuka, N., Minakuchi, H. and Nakanishi, K. (2006). "Size Exclusion Chromatography of Standard Polystyrenes with a Wide Range of Molecular Weight Up to 7.45 106 on Monolithic Silica Capillary columns." Polymer Journal 38(11): 1194-1197.

Fiscal Year 2007

Research Paper List
R. taguchi Group
  • Shindou H, Hishikawa D, Nakanishi H, Harayama T, Ishii S, Taguchi R, Shimizu T. “A single enzyme catalyzes both PAF production and membrane biogenesis of inflammatory cells: cloning and characterization of acetyl-CoA:lyso-PAF acetyltransferase”. J Biol Chem. 282, 6532-6539, 2007.
  • Hishikawa D, Shindou H, Kobayashi S, Nakanishi H, Taguchi R, Shimizu T., “Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity”. Proc Natl Acad Sci USA.; 105(8):2830-5. 2008.
  • Ogiso H, Suzuki T, Taguchi R., “Development of a reverse-phase liquid chromatography electrospray ionization mass spectrometry method for lipidomics, improving detection”. Anal Biochem.; 375(1):124-31. 2008.
  • Tsumoto H, Murata C, Miyata N, Kohda K, Taguchi R. “Efficient identification and quantification of proteins using isotope-coded 1-(6-methylnicotinoyloxy) succinimides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry”. Rapid Commun Mass Spectrom.; 21(23):3815-24, 2007.
  • Okuno T, Iizuka Y, Okazaki H, Yokomizo T, Taguchi R, Shimizu T: “12(S)-Hydroxyheptadeca-5Z, 8E, 10E-trienoic acid is a natural ligand for leukotriene B4 receptor 2”. Exp. Med. In press.

K. Hanada Group
  • Keigo Kumagai, Miyuki Kawano, Fumiko Shinkai-Ouchi, Masahiro Nishijima, and Kentaro Hanada: “Inter-organelle trafficking of ceramide is regulated by phosphorylation-dependent co-operativity between the PH and START domains of CERT”. J. Biol. Chem., 282, 17758-17766, 2007.
T. Yokomizo Group
  • Ando, K., Kawamura, Y., Akai, Y., Kunitomo, J., Yokomizo, T., Yamashita, M., Ohta, S., Ohishi, T., Ohishi, Y*. “Preparation of 2-, 3-, 4- and 7-(2-alkylcarbamoyl-1-alkylvinyl)benzo[b]furans and their BLT(1) and/or BLT(2) inhibitory activities”. Org. Biomol. Chem. 6, 296-307, 2008
  • Okuno T, Iizuka Y, Okazaki H, Yokomizo T*, Taguchi R, Shimizu T: “12(S)-Hydroxyheptadeca-5Z, 8E, 10E-trienoic acid is a natural ligand for leukotriene B4 receptor 2”. J. Exp. Med. In press.
T. Kobayashi Group
  • 相星淳一、小池薫、小林哲幸、大友康裕、山本保博 (2007) 出血性ショックに続発する多臓器不全のメカニズム−腸間膜リンパ液に対する保存血および代用血液の影響− 日本腹部救急医学会雑誌、27 (1): 51-57.
  • Yoko Nagasako-Akazome, Tomomasa Kanda, Yasuyuki Ohtake, Hiroyuki Shimasaki and Tetsuyuki Kobayashi (2007) “Apple polyphenols have an influence on fat metabolism in healthy subjects with relatively high body mass index”. Journal of Oleo Science, 56 (8): 417-428.
K. Yokoyama Group
  • Yokoyama K, Nakagawa M, Satoh M, Saitoh S, Dohmae N, Harada A, Satoh N, Karasawa K, Takio K, Yanagida M, Inoue K. Expression of a Novel 90-kDa Protein, Lsd90, Involved in the Metabolism of Very Long-chain Fatty Acid-containing Phospholipids in a Mitosis-defective Fission Yeast Mutant. Journal of Biochemistry、143巻、3号、369-375ページ、2008年
E. Fukuzaki Group
  • Kazuo Harada, Yohko Ohyama, Tetsuya Tabushi, Akio Kobayashi and Eiichiro Fukusaki, “Quantitative Analysis of Anionic Metabolites for Catharanthus roseus by Capillary Electrophoresis Using Sulfonated Capillary Coupled with Electrospray Ionization-Tandem Mass Spectrometry.”

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