In this research, we focus on the study of in vitro gametogenesis (IVG), which involves the creation of reproductive cells (e.g. sperm and eggs) from stem cells such as induced pluripotent stem cells (iPS cells) within a culture dish. We aim to identify and address the ethical, legal, and social issues (ELSI) associated with IVG for research purposes, which allows us to uncover valuable foundational knowledge by replicating phenomena that are otherwise challenging to study in vivo. However, IVG research also raises ethical questions, including the implications of creating children if the generation of human reproductive cells becomes successful in the future.
As we carry out our research, we keep in mind the regulations in the related field of assisted reproductive technology and are actively engaging non-experts such as public involvement panels to collaboratively examine the challenges of cutting-edge medical research in its foundational stages. In doing so, we propose a methodology that involves diverse stakeholders in the evaluation process. Furthermore, we collaborate with international experts to assess the ELSI concerns and governance mechanisms necessary for future IVG research, and aim to communicate these findings to policymakers, expert communities both domestically and internationally, and society at large.

・R&D Period： October 2023 - March 2026
・Grant Number： PMJRS23J1