ヒドラの共生微生物の研究で著名な Prof. Thomas Bosch (University of Kiel, Germany)にご講演いただきました。
Abstract：Rhythmic spontaneous contractions of body walls, such as those of the gastrointestinal tract, are a ubiquitous phenomenon in the animal kingdom. Studies in mice and humans have implied that intestinal dysmotility is associated with a disturbed microbiota, but the causal relationship has been unclear. Here, by applying experimental, flow physics and mathematical modelling approaches in the model Hydra, we provide functional evidence that reducing the frequency of spontaneous body wall contractions alters the fluid microenvironment near the tissue surface and thereby modifies the composition of the colonizing microbiota. Our findings suggest that spontaneous contractions of body walls enhance the transport of chemical compounds from and to the tissue surface where the bacteria reside, thus shaping and stabilizing the host-microbe associations.
ERATO Evolving Symbiosis Project International Seminar Series #08
Sponsored by ERATO FUKATSU Evolving Symbiosis Project
Co-sponsored by ERATO NOMURA Microbial Community Control Project
Co-sponsored by Grant-in-Aid for Scientific Research on Innovative Areas "Post-Koch Ecology”
Co-sponsored by Microbiology Research Center for Sustainability (MiCS), University of Tsukuba
Co-sponsored by Grant-in-Aid for Scientific Research on Innovative Areas "Constrained & Directional Evolution”