Strategic Sector
Creation of Basic Technology for the Realization of Leading Edge Measuring and Analytical Equipment through the Development of New Techniques, etc
Research Supervisor
Toshio Yanagida(Specially Appointed Professor, Osaka University)
Outline
This research field focuses on the construction of novel, fundamental measurement and analysis techniques for interpreting as yet unexplained life phenomena which are the driving force behind the development of life science technologies. Specifically, emphasis is placed on analysis techniques which reveal the true nature of the mechanism of interaction between organic molecules, which govern life phenomena, as well as techniques that can be used for in situ observations of biological entities or organic molecules inside cells, analysis techniques applicable at the level of individual cells, and novel measurement and analysis techniques applicable on any scale ranging from individual entities to entire ecosystems.Furthermore, novel techniques are sought for measuring and analyzing the influence exerted on biological entities by materials whose abundance in the environmental probes is extremely low.In addition, even for techniques based on existing fundamental principles, this field includes research which is expected to yield breakthrough research and life science technologies that can drastically improve the speed, sensitivity and resolution of measurements and analyses or can break the limitations associated with these factors. Such breakthroughs are also expected in the pursuit of new principles, and in the research and material science techniques related to the discovery and clarification of new phenomena.
Year Started : 2006
Yuji C. Sasaki
Professor, The University of Tokyo
Observations of Biomolecular Structural Recognition Process from Highly Accurate Individual Single Molecular Movies
Yoshikazu Nakayama
Professor, Osaka University
Measurement of Biological-single-molecule Dynamics by Carbon-nanotube Devices
Kuniaki Nagayama
Professor, National Institutes of Natural Sciences (NINS)
Development of ns-nm Resolution Electron- Photon Hybrid Microscope
Hideo Higuchi
Professor, The University of Tokyo
In Vivo Nano-imaging of Movement of Molecules in Mice
Atsuo Miyazawa
Professor, University of Hyogo
Biomolecular Tomography with Molecular Labels in the Cell
Year Started : 2005
Shigeru Aoyama
General Manager, OMRON Corp.
Investigation on the Enviornment Response of Biomolecule with Hybrid Localized SPR
Tetsuo Nagano
Professor, The University of Tokyo
Development and Application of Chemical Probes for Dynamic Visualization of Biomolecules
Yoshikazu Nakamura
Professor, The University of Tokyo
Multi-target Development of RNA-based 'Nanosensors' and 'Modulators'
Yusuke Mori
Professor, Osaka University
Creation of Perfect Protein Crystals
Yoshichika Yoshioka
Specially Appointed Professor, Osaka University
The Development of the Noninvasive Quantitative Brain Functional Imaging Technique
Year Started : 2004
Toshio Ando
Professor, Kanazawa University
Development of High-speed Imaging Apparatus for Studying Nanometer Scale Dynamic Behavior of Protein
Koji Ikuta
Professor, Nagoya University
New Principle Measurement Tools using Optical-driven Nano Machine
Masahiro Shirakawa
Professor, Kyoto University
Noninvasive Detection of Biomolecules in Living Organisms by Magnetic Resonance
Satoshi Takahashi
Professor, Tohoku University
Development of a New Observation Method for the Single Molecule Dynamics of Protein Folding
