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Creation of Perfect Protein Crystals

Research Project Outline

Technologies for creating high-quality crystals of proteins are necessary for the structural analysis of protein molecules, which will become important in the post-genome era. In this study, we aim to realize a novel system for creating a perfect crystal of proteins by advancing crystallizing technology based on new principles, such as generation of crystalline nuclei using femto-second laser irradiation and creating large, highquality crystals by stirring the solution. Using this system, it will then become possible to use X-ray structural analysis and neutron diffraction methods in order to identify the positions of water and hydrogen molecules in the active center of a protein.

Research Director
Professor, Osaka University
Research Started
Research Area
Novel Measuring and Analytical Technology Contributions to the Elucidation and Application of Life Phenomena
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