Research Director

Motonari Uesugi

Institute for Integrated Cell-Material Sciences, Kyoto University
Professor
website

Outline

Endogenous lipid molecules often have cryptic biological activities yet to be identified. Disclosure of these new activities, identification of the molecular targets, and their specific chemical modulation would contribute to both basic biological research and drug discovery.
Preliminary studies suggest such new functions of vitamin D derivatives and acyldopamins. This CREST project focuses on their molecular understanding and synthetic modulation with the goal of providing novel pharmacological approaches to treating metabolism disorders and cancers.