Project Homepage

Research Director: Toshiro Sato
(Professor, Keio University School of Medicine)
Research Term: Oct 2023 - Mar 2029
Grant Number: JPMJER2303

Organoids are structures that mimic living tissue and are established by culturing stem cells in specific environments. Organoids enable us to recapitulate gene expression and the self-organization of tissues. However, achieving functional maturation in organoids has proven extremely challenging, creating a bottleneck in our understanding of the multi-organ networks regulating human homeostasis.

Our project is dedicated to the development of ‘functional organoids’ that possess mature, organ-level functions at the cellular level. We are accomplishing this by developing novel cell culturing methods and a technological breakthrough for analyzing the physiological and biochemical functions of human tissues. Functional organoids hold the promise of advancing research into various biological phenomena and have significant potential for clinical applications, including drug development and regenerative medicine.

Research Groups

- Organoid development group
- Structure analysis group
- Metabolic analysis group
- Informatic analysis group

Project Headquarters

Keio University Center for Integrated Medical Research 7N6
35 Shinanomachi, Shinjuku-ku, Tokyo 160-0016