About inflammation

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Future prospects

A future view: Our research task

As mentioned above, a persistent inflammatory state, which does not subside, is referred to as chronic inflammation. However, are there any differences between chronic inflammation and acute inflammation? Why is inflammation sustained in chronic inflammation? Indeed, to explore a wide range of treatments for disease through elucidation of this mechanism and to control chronic inflammation are important aims of our research.

Future prospects

Our research areas promote the following projects aiming to create basic technologies that contribute to disease-detection at an early stage, and the control of chronic inflammation through an elucidation of the mechanisms responsible for chronicity of inflammation.

1) To identify the factors that induce and sustain chronic inflammation through elucidation of mechanistic failure of anti-inflammatory systems.

2) To create basic technologies that contribute to the control of some specific diseases, including cancers, neurodegenerative disorders, and arteriosclerotic diseases, through elucidation of the roles of chronic inflammation in these diseases.

3) To create basic technologies that allow early-stage detection and quantitative assessment of chronic inflammation.

We are trying to understand the regulatory mechanisms of highly complicated inflammation systems based on the integrated empirical findings from not only fundamental studies but also clinical studies. We hope that these efforts will contribute to the development of a basis for preemptive medical technologies that overcome a variety of diseases, which is increasing in incidence as a result of the progress in super-aging society, including cancers, arteriosclerotic diseases (myocardial infarction, cerebrovascular, etc.), neurodegenerative diseases (Alzheimer's disease, etc.), allergic diseases, and autoimmune diseases.

The 5 Cardinal Signs of Inflammation