[Chronic Inflammation] Elucidation and Control of the Mechanisms Underlying Chronic Inflammation

※ Affiliations and titles are as of the end of the research activity.

Strategic Objective

Creation of basic medical technologies for the prevention, diagnosis and treatment of cancer, arteriosclerotic diseases, and autoimmune disorders by the elucidation of the mechanisms underlying chronic inflammation

Research Supervisor

Kiyoshi Takatsu(Director, Toyama Prefectural Institute for Pharmaceutical Research)

Overview

 The purpose of this research is to elucidate the mechanisms through which inflammation becomes chronic, and to create basic technologies for the early detection, control, resolution, and reparation of chronic inflammation.

More specifically, this involves research aimed at: (1) identifying factors that induce and maintain the chronicity of inflammation by determining failure mechanisms of inflammation control; (2) clarifying the mechanisms through which specific diseases (including cancer, degenerative neurological disorders, and arteriosclerotic diseases) develop as a result of chronic inflammation, and to create basic technologies to control them; and (3) creating basic technologies that allow for the early detection and quantitative assessment of chronic inflammation. This not only involves established basic and clinical research, but also emphasizes research that sufficiently sublimes evidence-based findings for understanding higher order inflammation control mechanisms, and leads to the development of new preemptive basic medical technologies.

Research Area Advisors

Hajime Karasuyama
Masataka Sata
Noriko Sorimachi
Kazuyuki Tobe
Shigekazu Nagata
Yoshinori Fukui
Yasuhiro Furuichi
Masayuki Miura
Nobuyuki Miyasaka
Kohei Miyazono
Takashi Yamamura

Year Started: 2010

Researcher
Makoto Arita
Researcher
Tatsushi Igaki
Researcher
Naoko Ohtani
Researcher
Masatsugu Oh-Hora
Researcher
Shinobu Saijo
Researcher
Tomohiro Sawa
Researcher
Yuki Sugiura
Researcher
Kohsuke Takeda
Researcher
Norihiko Takeda
Researcher
Yasushi Hirota
Researcher
Kazuyo Moro
Researcher
Masakatsu Yamashita
Researcher
Hiroshi Watarai

Year Started: 2011

Researcher
Koji Aoki
Researcher
Kenichi Asano
Researcher
Koji Atarashi
Researcher
Takaharu Okada
Researcher
Junko Sasaki
Researcher
Katsuaki Sato
Researcher
Takashi Shichita
Researcher
Kazuhiro Suzuki
Researcher
Takashi Tanaka
Researcher
Susumu Nakae
Researcher
Sachie Hiratsuka
Researcher
Kumiko Makide
Researcher
Tohru Minamino
Researcher
Tadashi Yokosuka

Year Started: 2012

Researcher
Motoyuki Otsuka
Researcher
Hiroki Kato
Researcher
Takayuki Kuraishi
Researcher
Ai Koutani
Researcher
Takashi Saito
Researcher
Motoaki Sano
Researcher
Takayoshi Suganami
Researcher
Takahisa Nakamura
Researcher
Rikinari Hanayama
Researcher
Reo Maruyama

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