Presto Researcher

Outline

In order to understand the functions and characteristics of individual cells, it is essential to three-dimensionally visualize structural changes of intracellular biomolecules responsible for various biological activities. In this study, I will establish a fundamental bioimaging techniqe to visualize the 3D dynamics of intracellular biomolecules based on our previously developed “optically-detected magnetic resonance microscope” and molecular targeting approachs utilizing fluorescent nanodiamonds. Our bioimaging technique could be a breakthrough to uncover how mechanical/thermal signal is sensed by cells and transduced into cellular signaling pathways.