PRESTO Researcher

Research Outline

The oxidized fatty acids generated during oxidative stress or inflammatory conditions can react with proteins and form various adducts. These post-translational modifications of protein may serve as a good indicator of disease-associated conditions. In this study, we attempt to develop an analytic method for “the protein adductome”, representing the totality of covalent adducts bound to proteins. Such analytic method may be useful for various medical applications.