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The Creation of Basic Medical Technologies to Clarify and Control the Mechanisms Underlying Chronic Inflammation

Research Area Website

Strategic Sector

Creation of basic medical technologies for the prevention, diagnosis and treatment of cancer, arteriosclerotic diseases, and autoimmune disorders by the elucidation of the mechanisms underlying chronic inflammation

Research Supervisor

Masayuki Miyasaka (Professor, Osaka University)

Year Started

2010 

Outline

The purpose of this research is to elucidate the mechanisms through which inflammation becomes chronic, and the creation of basic technologies for the early detection, control, resolution, and reparation of chronic inflammation.
More specifically, this involves research aimed at
1) identifying factors that induce and maintain the chronicity of inflammation by determining failure mechanisms of inflammation control;
2) clarifying the mechanisms through which specific diseases (including cancer, degenerative neurological disorders, and arteriosclerotic diseases) develop as a result of chronic inflammation, and to create basic technologies to control them; and
3) creating basic technologies that allow the early detection and quantitative assessment of chronic inflammation. This not only involves established basic or clinical research, but also emphasizes on research that sufficiently sublimes evidence-based findings for understanding high-dimensional inflammation control mechanisms, and leads to the development of new preemptive basic medical technologies.



Year Started : 2011

Issei Komuro
Professor, Osaka University
Toshinori Nakayama
Professor, Chiba University
Osamu Nureki
Professor, The University of Tokyo
Mitsuru Matsumoto
Professor, Tokushima University
Kouji Yasutomo
Professor, Tokushima University
Masayuki Yamamoto
Professor, Tohoku University

Year Started : 2010

Hiroshi Asahara
Professor, Tokyo Medical and Dental University
Masaru Ishii
Professor, Osaka University
Kazuhide Inoue
Professor, Kyushu University
Hiroshi Kiyono
Professor, The University of Tokyo
Takashi Nagasawa
Professor, Kyoto University
Shuh Narumiya
Professor, Kyoto University
Kouji Matsushima
Professor, The University of Tokyo