Strategic Objective
Development of core technology platforms for understanding spatiotemporal multicellular interaction
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Research Supervisor

Michiyuki Matsuda (Professor, Graduate School of Biostudies, Kyoto University)
Overview
This CREST project aims to develop novel analytical technologies and theories that lead to the understanding of the dynamics of biosystems through spatiotemporal analysis of multicellular interactions and the development of technologies at the molecular or cellular levels.
With recent progress in omics and imaging technologies at the single cell level and in computer science, comprehensive and quantitative analysis of cells and biomolecules is becoming possible. This will lead to changes in life sciences methodologies in research that focuses on individual genes and molecules and in more complex analyses, such as targeting changes in many genes and molecules in single cells. However, there are many technological bottlenecks in the spatiotemporal analysis of cells and molecules, and in the three-dimensional analysis of tissues and organisms. Therefore, highly quantitative measurement methods and data analysis techniques that enable an understanding of spatiotemporal aspects of cellular and molecular dynamics in tissues and living organisms are required.
This project, thus, aims to develop new technologies and theories that contribute to the understanding of the spatiotemporal aspects of cellular and molecular networks and to promote research and development on the elucidation of multicellular dynamics. In addition, we will build technology platforms to predict and manipulate multicellular dynamics based on high-quality data and parameters obtained through this research and development.
Research Area Advisors
Kazuhiro Aoki |
Professor, National Institute for Basic Biology, National Institutes of Natural Sciences |
Tsuyoshi Akagi |
Senior Principal Scientist, Oncology Business Group medicine creation discovery oncology Tsukuba Research Laboratory, Eisai Co,,Ltd. |
Takafumi Inoue |
Professor, School of Science and Engineering, Waseda University |
Naoko Imamoto |
Chief Scientist, CPR, RIKEN |
Hiroyuki Kobayashi |
Vice President, New Business Promotion Department, Integrated Healthcare Disease Division, SHIONOGI & CO., LTD. |
Yumiko Saga |
Professor, Department of Gene Function and Phenomics, National Institute of Genetics |
Kazuhiro Sakurada |
Professor, School of medicine, Keio University |
Masaki Sano |
Professor, Institute of Natural Sciences, Shanghai Jiao Tong University |
Yutaka Suzuki |
Professor, Graduate School of Frontier Sciences, The Universitu of Tokyo |
Shin-ichi Tate |
Professor, Graduate School of Integrated Sciences for Life, Hiroshima University |
Masami Hirai |
Team Leader, Center for Sustainable Resource Science, RIKEN |
Masahiro Yamamoto |
Professor, Research Institute for Microbial Diseases, Osaka University |
Research Projects
- Year Started : 2019
- Year Started : 2020
- Year Started : 2021