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- [Itoshi Nikaido]Single-cell multi-omics technology to measure cell fate and function in tissues
Center for Biosystems Dynamics Research, RIKEN
Unit Leader
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Organs and tissues are maintained by stem cell growth, death, and differentiation. Identifying and analyzing stem cells in vivo is difficult because stem cell proliferation and differentiation are slow and rare. To find and analyze novel stem cells in organs and tissues, we should massively detect cell proliferation and differentiation in the same single cells in vivo. In this project, we will develop a novel method of single-cell sequencing to trace cell linage and define cell function in single cells. With our findings, our study seeks to promote the social well-being by contributing insights into how the health and longevity of organs can be achieved.