Theme 1: (1) Based on successfully identifying subtypes of healthy subjects using various psychiatric symptoms in collaboration with Theme 3, nine clinical evaluation scales were selected for items in a large-scale Internet/smartphone survey. Questionnaires on comfort and vitality were developed in collaboration with Theme 2 and the social implementation team to start data collection in the next fiscal year. We confirmed that the data structure was suitable for building the subtyping model. In collaboration with Theme 2, we conducted a preliminary survey after receiving approval from an ethics committee.

(2) In collaboration with Theme 3, we adopted the protocol for multicenter disease research of the Human Connectome Project, an international standard for developing brain data protocols. We have completed the construction of an environment that enables us to conduct the preprocessing pipeline for neuroimaging data.

There 2: A preliminary survey was conducted in preparation for a large-scale survey to construct high-low mix data in the next fiscal year and beyond. We confirmed that the created database was suitable for developing the subtyping model. In consultation with other research projects, we designed the experimental design, including the implementation period, subject segments, questionnaire items, and types of daily behavioral data (experience sampling and behavioral data) to be obtained. A data collection application was created, and a preliminary survey was conducted after receiving approval from an ethics committee. In the first stage, a screening questionnaire was administered to 50,000 participants, and 2,000 participants were selected based on their responses. In addition, approximately 100 respondents were selected among those who responded to the questionnaire, and a behavior measurement survey was conducted.