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【Research Acceleration Program】 In vivo detection of tiny tumors with novel photo-functional imaging probes

About Research Acceleration Program

In this program, remarkable outcomes obtained from the Strategic Basic Research Programs, which are expected to produce high-impact results within a next few years, are screened carefully for acceleration.
JST takes appropriate measures such as investing further research funds and extending research term.
It is important to provide such a flexible and additional funding in a timely manner in order to lead internationally acclaimed research results to innovation.

Project

 

  Title
  In vivo detection of tiny tumors with novel photo-functional imaging probes
  Research representative
  Yasuteru Urano
  Professor, Graduate School of Medicine, The University of Tokyo
  Research period
  January 2010 to December 2014

Outline
In this research program, novel fluorescence probes will be developed which afford the detection of tumors under fluorescence endoscope and open-stomach surgery within a few minutes, even when they are less than 1 mm in size, by topically spraying onto tissue surfaces that are suspected of harboring tumors. The efficacy of probes will be examined under the collaboration with many clinicians, by performing live fluorescent imaging of cancerous regions in freshly resected human tumor tissues. Novel fluorescence endoscopes suitable for these novel probes will be also developed. By combining these, state-of-the-art medical technology for tumor medicine will be created.

Homepage      http://cbmi.m.u-tokyo.ac.jp/

≪Other Projects≫

→ Identification of novel oncogenes in human cancer
 [Hiroyuki Mano (Professor, The University of Tokyo)]

→ The viral short transcripts is a candidate target detecting HIV early infection and monitoring ongoing viral replication in patients
 [Taketoshi Mizutani (Postdoctoral fellow, Microbial Chemistry Research Foundation)]

→ Development of low-voltage electron microscopes for atomic resolution analyses of functional materials and bio-molecules
 [Kazu Suenaga (Prime Senior Researcher, National Institute of Advanced Industrial Science and Technology (AIST))]

→ Membrane Protein Crystallography Project
 [So Iwata (Professor, Kyoto University / Imperial College London)]

Inquiry

E-mail:suishinf "at" jst.go.jp     replace "at" to @