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1. Y. Yamaguchi, N. Inukai, T. Narita, T. Wada and H. Handa
Evidence that NELF represses transcription elongation through binding to a DSIF/RNA polymerase II complex and RNA
Molecular and Cellular Biology Vol. 22 (9): 2918-2927 (2002)
2. K. Nakada, T. Ono and J. Hayashi
A novel defense system of mitochondria in mice and human subjects for preventing expression of mitochondrial dysfunction by pathogenic mutant mtDNAs
Mitochondrion Vol. 2: 59-70 (2002)
3. T. Shonai, M. Adachi, K. Sakata, M. Takekawa, T. Endo, K. Imai and M. Hareyama
MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells
Cell Death and Differentiation Vol. 9: 963-971 (2002)
4. N. Takahashi, T. Kawada, T. Yamamoto, T. Gotoh, A. Taimatsu, N. Aoki, H. Kawasaki, K. Taira, K. Yokoyama, Y. Kamei and T. Fushiki
Overexpression and ribozyme-mediated targeting of transcriptional coactivators, CREB binding protein(CBP) and p300, revealed their indispensable roles in adipocyte differentiation through the regulation of peroxisome proliferator- activated receptor-gamma(PPAR-gamma)
Journal of Biological Chemistry Vol. 277: 16906-16912 (2002)
5. C. Krawczyk, A. Olivera-dos-Santos, T. Sasaki, E. Griffiths, P. Ohashi, S. Snapper, F. Alt and J. Penninger
Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells
Immunity Vol.16: 331-343 (2002)
6. T. Sasaki, A. Suzuki, J. Sasaki and J. Penninger
Phosphoinositide 3-kinases in immunity: Lessons from knockout mice
Journal of Biochemistry Vol. 131: 495-501 (2002)
7. T. Muratani, T. Minami, U. Enomoto, M. Sakai, E. Okuda-Ashitaka, K. Kiyokane, H. Mori and S. Ito
Characterization of Nociceptin/Orphanin FQ-induced pain responses by the novel receptor antagonist N-(4-amino-2-methylquinolin-6-yl 9-2-(4-ethylphenoxymethyl) benzamide monohydrochloride.
J. Pharmacol. Exper. Ther. Vol. 303: 424-430 (2002)
8. S. Ikeda, H. Miyazaki, T. Nakatani, Y. Kai, Y. Kamei, S. Miura, N. Tsuboyama-Kasaoka and O. Ezaki
Up-regulation of SREBP-1c and lipogenic gene in skeletal muscles after exercise training
Biochemical and Biophysical Research Communications Vol. 296: 395-400 (2002)
9. K. Inoue, H. Osaka, Virginia C. Thurston, Joe T. R. Clarke, A. Yoneyama, Lisa Rosenbarker, Thomas D. Bird, M. E. Hodes, Lisa G. Shaffer and James R. Lupkin
Genomic rearrangements Resulting in PLP1 Deletion Occur by Nonhomologous end joining and Cause Different Dysmyelinating Phenotypes in Males and Females
Am. J. Hum. Genet. Vol. 71 (4): 838-853 (2002)
10. M. Yamazaki, H. Miyazaki, H. Watanabe, T. Sasaki, T. Maehama, M. Frohman and Y. Kanaho
Phosphatidylinositol 4-phosphate 5-kinase is essential for ROCK-mediated neurite remodeling
Journal of Biological Chemistry Vol. 277: 17226-17230 (2002)
11. N. Ito, T. Yokomizo, T. Sasaki, H. Kurosu, J. Penninger, Y. Kanaho, T. Katada, K. Hanaoka and T. Shimizu
Requirement of phosphatidylinositol 3-kinase-activation and Ca influx for leukotriene B4-induced enzyme release
Journal of Biological Chemistry Vol. 277: 44898-44904 (2002)
12. M. Crackower, G. Oudit, I. Kozieradzki1, R. Sarao, T. Sasaki, E. Hirsch, A. Suzuki, T. Shioi, J. Sasaki, R. Sah, H. Cheng, V. Rybin, G. Lembo, L. Fratta, A. Oliveira-dos-Santos, J. Benovic, R. Kahn1, S. Izumo, S. Steinberg, M. Wymann, P. Backx, and J. Penninger
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathway
Cell Vol. 110: 737-749 (2002)
13. K. Nakamura, K. Tanoue, T. Satoh, M. Takekawa, M. Watanabe, H. Shima and K. Kikuchi
A novel low-molecular-mass dual-specificity phosphatase, LDP-2, with a naturally occurred substitution that affects substrate specificity.
J. Biochem. Vol.132: 463-470 (2002)
14. T. Abe, T. Suzuki, S. Ito, M. Unno, T. Onogawa and T. Tokui
The human hepatocyte-specific organic anion transporter encoded by the SLC21A8 gene
Gastroenterology Vol. 122: 1545-1546 (2002)
15. Y. Kamei, J. Mizukami, S. Miura, M. Suzuki, N. Takahashi, T. Kawada, T. Taniguchi and O. Ezaki
A forkhead transcription factor FKHR up-regulates lipoprotein lipase expression in skeletal muscle
FEBS Letters Vol. 536: 232−236(2003)
16. M. Takekawa, K. Tatebayashi, F. Itoh, M. Adachi, K. Imai and H. Saito
Smad-dependent GADD45β expression mediates delayed activation of p38 MAP kinase by TGF-β
The EMBO Journal Vol. 21: 6473-6482(2002)
17. S. Mitsuhashi, H. Shima, N. Tamura, N. Matsuura, M. Takekawa, T. Urano, M. Ubukata and K. Kikuchi
Usage of tautomycetin, a novel inhibitor of protein phosphatase 1(PP1) reveals that PP1 is a positive regulator of Raf-1 in COS-7 cells.
Journal of Biological Chemistry Vol. 278: 82-88(2003)
18. 佐々木雄彦
実験医学 Vol. 20: 18 (2002)
19. T. Mabuchi, S. Matsumura, E. Okuda-Ashitaka, T. Kitano, H. Kojima, T. Nagano, T. Minami and S. Ito
Attenuation of neuropathic pain by nociceptin/orphanin FQ antagonist is mediated by inhibition of nitric oxide production
Eur. J. Neurosci. Vol. 17: 1384-1392(2003)
20. S. Sakon, X. Xue, M. Takekawa, T. Okazaki, Y. Kojima, J-H. Pia, T. Sasazuki, H. Yagita, K. Okumura, T. Doi and H. Nakano
NK-kappa B inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death
The EMBO Journal Vol. 22: 3898-3909(2003)
21. K. Tatebayashi, M. Takekawa and H. Saito
A docking site that determining specificity of Pbs2 MAPKK to Ssk2/Ssk22 MAPKKKs in yeast HOG pathway
The EMBO Journal Vol. 22: 3624-3634(2003)
22. 吉田秀郎、松居利江、細川暢子、Randal J. Kaufman、永田和宏、森和俊
A Time-dependent phase shift in the mammalian unfolded protein response
Developmental Cell Vol. 4: 265-271 (2003)
23. T. Narita, Y. Yamaguchi, K. Yano, S. Sugimoto, S. Chanarat, T. Wada, D. Kim, J. Hasegawa, M. Omori, N. Inukai, M. Endoh, T. Yamada and H. Handa
Human transcription elongation factor NELF: Identification of novel subunits and reconstitution of the functionally active complex
Molecular and Cellular Biology Vol. 23 : 1863-1873, 2003.
24. Y. Ohba, K. Kurokawa and M. Matsuda
Mechanism of the spatio-temporal regulation of Ras and Rap1
The EMBO Journal Vol. 22(4): 859-869(2003)
25. C. H. Wu, Y. Yamaguchi, L. Benjamin, M. Horvat-Gordon, J. Washinski, E. Enerly, J. Larsson, A. Lambertsson, H. Handa and D. S. Gilmour
NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila.
Genes and Development Vol. 17 (11): 1402-1414(2003)
26. U. Watanabe, T. Shimura, N. Sako, J. Kitagawa, T. Shingai, E. Watanabe, M. Noda and T. Yamamoto
A comparison of voluntary salt-intake behavior in Nax-gene deficient and wild-type mice with reference to peripheral taste inputs.
Brain Reserch Vol. 967: 247-256(2003)
27. M. Yoshizawa, M. Sone, N. Matsuo, T. Nagase, O. Ohara, Y. Nabeshima and M. Hoshino
Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain
Gene Expression Patterns Vol. 3: 375-381(2003)
28. A. Suzuki, S. Itami, M. Ohishi, K. Hamada, T. Inoue, N. Komazawa, H. Senoo, T. Sasaki, J. Takeda, M. Manabe, T. Mak and T. Nakano
Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation
Cancer Research Vol. 63: 674-681(2003)
29. J. Irie-Sasaki, T. Sasaki and J. M. Penninger
CD45-regulated signaling pathways
Current Topics Medical Chemistry Vol. 3: 783-796(2003)
30. M. Nogami, M. Yamazaki, H. Watanabe, Y. Okabayashi, Y. Kido, M. Kasuga, T. Sasaki, T. Maehama and Y. Kanaho
Requirement of autophosphorylated tyrosine 992 of EGF receptor and docking protein phospholipase Cγ1 for membrane ruffle formation
FEBS Letter Vol. 536: 71-76(2003)
31. H. Kishimoto, K. Nakagawa, T. Watanabe, D. Kitagawa, H. Momose, J. Seo, G. Nishitai, N. Shimizu, S. Ohata, S. Tanemura, S. Asaka, T. Goto, H. Fukushi, H. Yoshida, A. Suzuki, T. Sasaki, T. Wada, J. Penninger, H. Nishina and T. Katada
Different properties of SEK1 and MKK7 in dual phosphorylation of stress-induced activated protein kinase SAPK/JNK in embryonic stem cells.
Journal of Biological Chemistry Vol. 278: 16595-16601(2003)
32. A. Suzuki, T. Kaisho, M. Ohishi, M. Tsukio-Yamaguchi, T. Tsubata, PA. Koni, T. Sasaki, TW Mak and T. Nakano
Critical roles of Pten in B cell homeostatis and immunoglobulin class switch recombination
Journal of Experimental Medicine Vol. 197: 657-667(2003)
33. H. Kishimoto, K. Hamada, M. Saunders, S. Backman, T. Sasaki, T. Nakano, T. Mak and A. Suzuki
Physiological functions of Pten in mouse tissues
Cell Structure and Function
34. A. Kim, T. Sasaki and M. Chano
JNK interacting protein 1 promotes Akt1 activation
Journal of Biological Chemistry Vol. 278: 29830-29836, 2003.
35. K. Nishikawa, Hang Li, R. Kawamura, H. Osaka, Yu-Lai Wang, Y. Hara, T. Hirokawa, Y. Manago, T. Amano, M. Noda, S. Aoki and K. Wada
Alterations of structure and hydrolase activity of parkinsonism-associated human ubiquitin carboxyl-terminal hydrolase L1 variants
Biochemical and Biophysical Research Communications Vol. 304: 176-183(2003)
36. H. Osaka, Y.-L. Wang, K. Tanaka, S. Takizawa, R. Setsuie, Hang Li, Y. Sato, K. Nishikawa, Ying-Jie Sun, M. Sakurai, T. Harada, Y. Hara, I. Kimura, S. Chiba, K. Namikawa, H. Kiyama, M. Noda, S. Aoki and K. Wada
Ubiquitin carboxy-terminal hydrolase L1 binds to and satabilizes monoubiquitin in neuron
Human Molecular Genetics Vol. 12: 1945-1958(2003)
37. T. Iwawaki, R. Akai, K. Kohno and M. Miura
A transgenic mouse model for monitoring endoplasmic reticulum stress
Nature Medicine Vol. 10: 98-102(2004)
38. A. Satoh, M.Toyota, F. Itoh, Y. Sasaki, H. Suzuki, K. Ogi, T. Kikuchi, H. Mita, T. Yamashita, T. Kojima, M. Kusano, M. Fujita, M. Hosokawa, T. Endo, T. Tokino and K. Imai
Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer
Cancer Research Vol. 63: 8606-8613(2003)
39. A. Sakakibara, Y. Ohba, K. Kurokawa., M. Matsuda and S. Hattori
Novel function of Chat in controlling cell adhesion via Cas-Crk-C3G-pathway-mediated Rap1 activation
Journal of Cell Science Vol. 115(Pt24): 4915-4924(2002)
40. R. E. Itoh, K. Kurokawa, Y. Ohba, H. Yoshizaki, N. Mochizuki, and M. Matsuda
Activation of Rac and Cdc42 video-imaged by FRET-based single-molecule probes in the membrane of living cells
Molecular and Cellullar Biology Vol. 22(18): 6582-6591(2002)
41. H. Yoshizaki, Y. Ohba, K. Kurokawa, R. E. Itoh, T. Nakamura, N. Mochizuki, K. Nagashima and M. Matsuda
Activity of Rho-family GTPases during cell division as cisualized with FRET-based probes
Journal of Cell Biology Vol. 162(2): 223-232(2003)
42. S. Giuriato, C. Pesesse, S. Bodin, T. Sasaki, C. Viala, E. Marion, J. Penninger, S. Schurmans, C. Erneux and B. Payrastre
SH2 domain containing inositol 5-phosphatase 1 and 2 in blood platelets: interaction and respective role in the control of phosphatidylinositol 3,4,5-trisphosphate level
Biochemical Journal Vol. 376: 199-207(2003)
43. G. Oudit, M. Crackower, U. Eriksson, R. Sarao, I. Kozieradzki, T. Sasaki, J. Sasaki, D. Gidrewicz, V. Rybin, T. Wada, S. Steinberg, P. Backx and J. Penninger
Phosphoinositide 3-kinaseγ-deficient mice are protected from isoproterenol-induced heart failure
Circulation Vol. 108: 2147-2152(2003)
44. M. Woo, R. Hakem, C. Furlonger, A. Hakem, G. Duncan, T. Sasaki, D. Bouchard, L. Lu, G. Wu, C. Paige and T. Mak
Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity
Nat. Immunol. Vol. 4: 1016-1022(2003)
45. I. Khan, H. Osaka, S. Stanislaus, R.M. Calvo, T. Deerinck, T.L. Yaksh TL and P. Taylor
Nicotinic acetylcholine receptor distribution in relation to spinal neurotransmission pathways
J. Comp. Neurol. Vol. 467(1): 44-59(2003)
46. T. Harada, C. Harada, Y.L. Wang, H. Osaka, K. Amanai, K. Tanaka, S. Takizawa, R. Setsuie, M. Sakurai, Y. Sato, M. Noda and K. Wada
Role of ubiquitin carboxy terminal hydrolase-LS1 in neural cell apoptosis induced by ischemic retinal injury in vivo
Am. J. Pathol. Vo. 164(1): 59-64(2004)
47. H. Kusuhara, Z. He, Y. Nagata, Y. Nozaki, T. Ito, H. Masuda, P.J. Meier, T. Abe and Y. Sugiyama
Expression and functional involvement of organic anion transporting polypeptide subtype 3 (Slc21a7) in rat choroid plexus
Pharm. Res. Vol. 20: 720-727( 2003)
48. T. Suzuki, T. Onogawa, N. Asano, H. Mizutamari, T. Mikkaichi, M. Tanemoto, M. Abe, F. Satoh, M. Unno, K. Nunoki, M. Suzuki, T. Hishinuma, J. Goto, T. Shimosegawa, S. Matsuno, S. Ito and T. Abe
Identification and characterization of novel rat and human gonad specific organic anion transporters
Mol. Endocrinol. Vol. 17: 1203-1215( 2003)
49. S. Ohtsuki, T. Takizawa, H. Takanaga, N. Terasaki, T. Kitazawa, S. Sasaki, T. Abe, K. Hosoya, and T. Terasaki
In vitro study of the functional expression of organic anion transporting polypeptide 3 at rat choroid plexus epithelial cells and its involvement in the cerebrospinal fluid-to-blood transport of estrone-3-sulfate
Mol. Pharmacol. Vol. 63: 532-537(2003)
50. K. Sato, J. Sugawara, T. Sato, H. Mizutamari, T. Suzuki, A. Ito, T. Mikkaichi, T. Onogawa, M. Tanemoto, M. Unno, T. Abe and K. Okamura
Expression of organic anion transporting polypeptide E (OATP-E) in human placenta.
Placenta Vol. 24: 144-148( 2003)
51. T. Kodawara, S. Masuda, H. Wakasugi, Y. Uwai, T. Futami, H. Saito, T. Abe and K. Inu
Organic anion transporter oatp2-mediated interaction between digoxin and amiodarone in the rat liver.
Pharmaceutical Res. Vol. 19: 738-43( 2002)
52. Y. Shitara, D. Sugiyama, H. Kusuhara, Y. Kato, T. Abe, P.J. Meier, T. Itoh and Y. Sugiyama
Comparative inhibitory effects of different compounds on rat oatp1 (slc21a1)- and oatp2 (Slc21a5)-mediated transport.
Pharmaceutical Res. Vol. 19: 147-153 ( 2002)
53. A. Ito, K. Yamaguchi, T. Onogawa, M. Unno, T. Suzuki, T. Nishio, T. Suzuki, H. Sasano, T. Abe, and M. Tamai.
Distribution of organic anion-transporting polypeptide 2 (oatp2) and oatp3 in the rat retina.
Invest. Ophthalmol. Vis. Sci. Vol. 43: 858-863( 2002)
54. M. Sasaki, H. Suzuki, K. Ito, T. Abe and Y. Sugiyama
Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and multidrug resistance-associated protein 2 (MRP2/ABCC2).
J. Biol. Chem. Vol. 277: 6497-6503( 2002)
55. D. Sugiyama, H. Kusuhara, Y. Shitara, T. Abe and Y. Sugiyama
Effect of 17beta-estradiol-D-17beta-glucuronide on the rat organic anion transporting polypeptide 2-mediated transport differs depending on substrates
Drug Metab. Dispos. Vol. 30: 220-223( 2002)
56. T. Kodawara, S. Masuda, H. Wakasugi, Y. Uwai, T. Futami, H. Saito, T. Abe and K. Inu
Organic anion transporter oatp2-mediated interaction between digoxin and amiodarone in the rat liver
Pharmaceutical Res. Vol. 19: 738-743( 2002)
57. H. Sakurai, S. Gunji, F. Tokanai, Y. Inoue, T. Maeda and T. Masuda
Detection of Photoabsorption Point with Capillary Imaging Gas Proportional Counter
IEEE Nucl. Sci. Vol. 49(3): 1560- 1565, 2002.
58. H. Sakurai, S. Gunji, F. Tokanai, T. Maeda, N. Ujiie and N. Saitoh
Characteristics of an X-ray Imaging Detecteor with Double Capillary Plates
Nucl. Instr. and Meth. A Vol. 513: 282-286(2003)
59. H. Sakurai, S. Gunji, F. Tokanai, T. Maeda, N. Ujiie and N. Saitoh
Photoelectron Track Image of Capillary Gas Proportional Counter
Nucl. Instr. and Meth. A Vol. 505: 219-222(2003)
60. Unno, M., Abe, T, Onogawa, T., Adachi, H., Ando, T., Ohtsuka, H., Sato, T., Katayose, Y., Suzuki, M. and Matsuno, S.
Functional analysis using adenovirus-mediated over-expression of liver-specific organic anion transporter, LST-1/OATP-C/OATP2 and LST-2/OATP8.
Hepatology, Vol. 36: 1121 Part 2 Suppl. S, 2002.
61. Adachi, H., Suzuki, T., Abe, M., Asano, N., Mizutamari, H., Tanemoto, M., Nishio, T., Onogawa, T., Toyohara, T., Kasai, S., Satoh, F., Suzuki, M., Tokui, T., Unno, M., Shimosegawa, T., Matsuno, S., Ito, S. and Abe, T.
Molecular characterization of human and rat organic anion transporter OATP-D.
Am. J. Physiol, Vol. 285: F1188-1197, 2003.
62. Hagiwara, K., Nunoki, K., Ishii, K., Abe, T. and Yanagisawa, T
Differential inhibition of the transient outward currents of Kv1.4 and Kv4.3 by endothelin.
Biochem. Biophys. Res. Commun, Vol. 310: 634-640, 2003.
63. Tanemoto, M., Abe, T., Obara, N., Abe, M, Satoh, F. and Ito, S.
Successful treatment of severe hypertension with combination of angiotensin converting enzyme inhibitor and angiotensin II receptor blocker.
Hypertension Res, Vol. 26: 863-868, 2003.
64. Ito, A., Yamaguchi, K., Tomita, H., Suzuki, T, Tohru, O., Sato, T., H., Mikkaichi, T., Nishio, T., Suzuki, T., Unno, M., Sasano, H., Abe, T. and Tamai, M.
Distribution of rat organic anion transporting polypeptide -E (oatp-E) in the rat eye.
Invest. Ophthalmol. Vis. Sci, Vol. 44: 4877-4884, 2003.
65. Arima, S., Kohagura, K., Xu, H.L., Sugawara, A., Abe, T., Satoh, F., Takeuchi, K. and Ito, S.
Nongenomic vascular action of aldosterone in the glomerular microcirculation.
J. Am. Soc. Nephrol, Vol. 14: 2255-2263, 2003.
66. I. Kuraoka, M. Endou, Y. Yamaguchi, T. Yamada, H. Handa and K. Tanaka
Effects of endogeneous DNA base lesions on transcription elongation by mammalian RNA polymerase II.
J. Biol. Chem, Vol. 278: 7294-7299, 2003.
67. T. Okada, K. Haze, S. Nadanaka, H. Yoshida, N. G. Seidah, Y. Hirano, R. Sato, M. Negishi and K. Mori
A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6.
J. Biol. Chem, Vol. 278: 31024-31032, 2003.
68. R. Kumar, G. S. Krause, H. Yoshida, K. Mori and D. J. DeGracia
Dysfunction of the unfolded protein response during global brain ischemia and reperfusion.
J. Cereb. Blood Flow Metab, Vol. 23: 462-471, 2003.
69. Unno, M. and Abe, T.
Similarity and dissimilarity of LST-1/OATP2/OATP-C (SLC21A6) and OATP8/LST-2 (SLC21A8).
J. Gastroenterol, Vol. 38: 108-109, 2003.
70. K. Ishii and U. K. Laemmli
Structural and dynamic functions establish chromatin domains.
Molecular Cell, Vol. 11: 237-248, 2003.
71. H. Hirai,T. Launey, S. Mikawa, T. Torashima, D. Yanagihara, T. Kasaura, A. Miyamoto and M. Yuzaki
New role of δ2-glutamate receptors in AMPA receptor trafficking and cerebellar function.
Nature Neuroscience, Vol. 6: 869-876, 2003.
72. T. Otsuji, E. Okuda-Ashitaka, S. Kojima, H. Akiyama, S. Ito and Y. Ohmiya
Monitoring for dynamic biological processing by intra-molecular bioluminescence resonance energy transfersystem using secreted luciferase.
Anal. Biochem, Vol. 329: 230-237, 2004.
73. S. Verma, A. M. Shewan, J. A. Scott, F. M. Helwani, N. R. Den Elzen, H. Miki, T. Takenawa and A. S. Yap
Arp2/3 activity is necessary for efficient formation of E-cadherin adhesive contacts.
Biochem. J, Vol. 279: 34062-34071, 2004.
74. K. Takenaka, H. Nakagawa, S. Miyamoto and H. Miki
The pre-mRNA splicing factor SF3a66 functions as a microtuble binding and bundling protein.
Biochem. J, Vol. 382: 223-230, 2004.
75. K. Takagaki, T. Satoh, N. Tanuma, K. Masuda, M. Takekawa, H. Shima and K. Kikuchi
Characterization of a novel low-molecular-mass dual-specificity phosphatase 3 that enhances activation of JNK and p38.
Biochem. J, Vol. 383, 447-455, 2004.
76. Y. L. Wang, A. Takeda, H. Osaka, Y. Hara, A. Furuta, R. Setsuie, Y. J. Sun, J. Kwon, Y. Sato, M. Sakurai, M. Noda, Y. Yoshikawa and K. Wada
Accumulation of beta- and gamma-synucleins in the ubiquitin carboxyl-terminal hydrolase L1-deficient gad mouse.
Brain Res, Vol. 1019: 1-9. 2004.
77. T. Ono, Y. Kasahara, K. Nakada and J. -I.. Hayashi
Presence of interaction but not complementation between human mtDNAs carrying different mutations within a tRNALeu(UUR) gene.
Biochem. Biophys. Res. Commun, Vol. 314: 1107-1112, 2004.
78. K. Nakada, A. Sato, H. Sone, A. Kasahara, K. Ikeda, Y. Kagawa, H. Yonekawa and J. -I. Hayashi
Accumulation of pathogenic delta-mtDNA induced deafness but not diabetic phenotypes in mito-mice.
Biochem. Biophys. Res. Commun, Vol. 323: 175-184, 2004.
79. Y. Funato, T. Terabayashi, N. Suenaga, M. Seiki, T. Takenawa and H. Miki
IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasiveness.
Cancer Res, Vol. 64: 5237-5244, 2004.
80. L. Romero-Ramirez, H. Gao, D. Nelson, E. Hammond, A. H. Lee, H. Yoshida, K. Mori, L. H. Glimcher, N. C. Denko and A. Giaccia
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.
Cancer Res, Vol. 64: 5943-5947, 2004.
81. J. Nagai, T. Yazawa, K. Okudera, T. Ito, H. Kigasawa, H. Kitamura and H. Osaka
Retinoic acid induce cell death on neuroblastoma cell lines by inhibition of proteasome-dependent degradation of retinoic acid receptor α.
Cancer Res, Vol. 64: 7910-7917, 2004.
82. B.H. Jennings, S. Shah, Y. Yamaguchi, M. Seki, R.G. Phillips, H. Handa and D. Ish-Horowics
Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila.
Curr. Biol, Vol. 14: 1680-1684, 2004.
83. H. Chi, B. Ku, M. Takekawa, R. J. Davis and R. A. Flavell
GADD45β/GADD45γand MEKK4 comprise a genetic pathway mediating STAT4-independent IFNγ production in T cells.
EMBO J, Vo. 23: 1576-1586, 2004.
84. J. Nozaki, H. Kubota, H. Yoshida, M. Naitoh, J. Goji, T. Yoshinaga, K. Mori, A. Koizumi and K. Nagata
The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita.
Genes Cells, Vol. 9: 261-270, 2004.
85. S..E. Aiyar, J.-L Sun, A..L. Blair, C..A. Moskaluk, Y. Lv, Q.-N. Ye, Y. Yamaguchi, A. Mukherjee, D.-M. Ren, H. Handa and R. Li
Attenuation of estrogen receptor α-mediated transcription through estrogen-stimulated recruitment of a negative elongation factor.
Genes Dev, Vo.18: 2134-2146, 2004.
86. A. Sato, K. Nakada, H. Shitara, H. Yonekawa and J. -I. Hayashi
In vivo Interaction between mitochondria carrying mtDNAs from different mouse species.
Genetics, Vol. 167: 1855-1861, 2004.
87. C.-S. Chen, R. Matsuoka, S. Arai, Y. Momiyama, H. Murakami, s.-Y. Kuno, K. Ishikawa, K. Nakada, M. Tawata and J.-I. Hayashi
Determination of normal ranges of mitochondial respiratory activties by mtDNA transfer from 54 human subjects to mtDNA-less Hela cells for identification of the pathogenicities of mutated mtDNAs.
J. Biochem, Vol. 135: 237-243, 2004.
88. K. Yamamoto, H. Yoshida, K. Kokame, P. J. Kaufman and K. Mori
Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II.
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