※ Affiliations and titles are as of the end of the research activity.
Strategic Objective
Creation of basic medical technologies for the prevention, diagnosis and treatment of cancer, arteriosclerotic diseases, and autoimmune disorders by the elucidation of the mechanisms underlying chronic inflammation
Research Supervisor
Masayuki Miyasaka（Professor Emeritus, Osaka University）
Overview
The purpose of this research is to elucidate the mechanisms through which inflammation becomes chronic, and to create basic technologies for the early detection, control, resolution, and reparation of chronic inflammation.
More specifically, this involves research aimed at: (1) identifying factors that induce and maintain the chronicity of inflammation by determining failure mechanisms of inflammation control; (2) clarifying the mechanisms through which specific diseases (including cancer, degenerative neurological disorders, and arteriosclerotic diseases) develop as a result of chronic inflammation, and to create basic technologies to control them; and (3) creating basic technologies that allow for the early detection and quantitative assessment of chronic inflammation. This not only involves established basic and clinical research, but also emphasizes research that sufficiently sublimes evidence-based findings for understanding higher order inflammation control mechanisms, and leads to the development of new preemptive basic medical technologies.
More specifically, this involves research aimed at: (1) identifying factors that induce and maintain the chronicity of inflammation by determining failure mechanisms of inflammation control; (2) clarifying the mechanisms through which specific diseases (including cancer, degenerative neurological disorders, and arteriosclerotic diseases) develop as a result of chronic inflammation, and to create basic technologies to control them; and (3) creating basic technologies that allow for the early detection and quantitative assessment of chronic inflammation. This not only involves established basic and clinical research, but also emphasizes research that sufficiently sublimes evidence-based findings for understanding higher order inflammation control mechanisms, and leads to the development of new preemptive basic medical technologies.
Research Area Advisors
| Nobuya Inagaki |
| Takeshi Imamura |
| Satoshi Uematsu |
| Yoshiyuki Ohsugi |
| Shosei Koh |
| Hiroshi Takayanagi |
| Keiko Yamauchi-Takihara |
| Masayuki Murakami |
| Takehiko Yokomizo |
| Akihiko Yoshimura |
Year Started: 2010
Research Director
Hiroshi Asahara (Professor, Tokyo Medical and Dental University)
- Takada Shuji
Research Director
Masaru Ishii (Professor, Osaka University)
Research Director
Kazuhide Inoue (Professor, Kyushu University)
- Keiko Ohsawa
- Hiroshi Kiyama (Professor, Nagoya University)
- Hiroshi Nakanishi (Professor, Kyushu University)
Research Director
Hiroshi Kiyono (Professor, The University of Tokyo)
- Ichiro Takahashi (Professor, Hiroshima University)
- Ivaylo Ivanov (Columbia University（USA）)
Research Director
Takashi Nagasawa (Professor, Institute for Frontier Medical Sciences, Kyoto University)
Research Director
Shuh Narumiya (Graduate School of Medicine, Kyoto University)
- Fumitaka Ushikubi (Professor, Faculty of Medicine, Asahikawa Medical University)
- Takuya Kobayashi (Graduate School of Medicine, Kyoto University)
Research Director
Koji Matsushima (Professor)
- Yutaka Inagaki (Professor, Faculty of Medicine, Tokai University)
- Hitoshi Kohsaka (Professor, Tokyo Medical and Dental University)
- Osamu Yoshie (Professor, Faculty of Medicine, Kindai University)
- Takashi Wada (Professor, Kanazawa University)
Year Started: 2011
Research Director
Issei Komuro (Professor, The University of Tokyo)
- Hiroshi Akazawa (Graduate School of Medicine and Faculty of Medicine, The University of Tokyo)
- Jong-Kook Lee (Graduate School of Medicine Faculty of Medicine, Osaka University)
Research Director
Toshinori Nakayama (Professor, Chiba University)
Research Director
Osamu Nureki (Professor, Garaduate school of Science, The University of Tokyo)
- Junken Aoki (Professor, Tohoku University)
- Fuminori Tokunaga (Professor, Gunma University)
Research Director
Mitsuru Matsumoto (Professor, Tokushima University)
Research Director
Koji Yasutomo (Professor, Tokushima University)
- Yasuhiko Nishioka (Professor, Tokushima University)
Research Director
Masayuki Yamamoto (Professor, Tohoku University)
- Nobuyuki Tanaka (Head, Division of Cancer Biology and Therapeutics, Miyagi Cancer Center, Research Institute)
- Hozumi Motohashi (Professor, IDAC, Tohoku University)
