※ Affiliations and titles are as of the end of the research activity.
Research Supervisor
Kazuo Sugamura（Chief Director, Miyagi Prefectural Hospital Organization）
Overview
This research area aims to improve prevention, diagnosis, and treatment of human immunological diseases, centered on allergic and autoimmune diseases, and includes research for development of basic technologies for improvement of appropriate functioning of the immune system.
Diseases centered on allergic responses and autoimmune systems vary from those that may lower the quality of life (QOL) of patients to those leading to death in serious cases. Deepened understanding of the immune mechanism and control of such diseases at levels of molecules, cells, organs, and tissues will be evolved into understanding of a higher-level control immune network system at individual levels, leading to clinical application.
Specific examples of research projects include immunoregulatory mechanisms by regulatory cells, construction mechanisms of the mucous membrane immune system, autoimmune system, acquired immune system, and natural immune system and their control, etiological mechanisms of autoimmune and allergic diseases, immune and infection control mechanisms, development of drugs and vaccines against diseases and measurement of their effects, establishment of methods for diagnosis and treatment of diseases, and so forth.
Diseases centered on allergic responses and autoimmune systems vary from those that may lower the quality of life (QOL) of patients to those leading to death in serious cases. Deepened understanding of the immune mechanism and control of such diseases at levels of molecules, cells, organs, and tissues will be evolved into understanding of a higher-level control immune network system at individual levels, leading to clinical application.
Specific examples of research projects include immunoregulatory mechanisms by regulatory cells, construction mechanisms of the mucous membrane immune system, autoimmune system, acquired immune system, and natural immune system and their control, etiological mechanisms of autoimmune and allergic diseases, immune and infection control mechanisms, development of drugs and vaccines against diseases and measurement of their effects, establishment of methods for diagnosis and treatment of diseases, and so forth.
Research Area Advisors
| Takashi Saito |
| Shimon Sakaguchi |
| Takeshi Sasaki |
| Kazuko Shibuya |
| Kiyoshi Takatsu |
| Takeshi Tokuhisa |
| Masato Nose |
| Nobuo Hanai |
| Nobuyuki Miyasaka |
Year Started: 2008
Research Director
Yoichiro Iwakura (The University of Tokyo)
Research Director
Toshiaki Ohteki (Professor, Tokyo Medical and Dental University)
- Kayo Inaba (Professor, Graduate School of BIOSTUDIES, Kyoto University)
- Makoto Iwata (Professor)
- Norimitsu Kadowaki (Graduate School of Medicine, Kyoto University)
Research Director
Toshiyuki Takai (Professor, Tohoku University)
Research Director
Shigekazu Nagata (Osaka University)
Research Director
Toshio Hirano (National Institutes for Quantum and Radiological Science and Technology)
- Daisuke Kamimura (Osaka University)
- Masaaki Murakami (Professor, Institute for Generic Medicine, Hokkaido University)
Research Director
Yoshinori Fukui (Professor, Medical Institute of Bioregulation, Kyushu University)
- Shuichi Tawara (Astellas Pharma Inc.)
- Kiyoshi Furuichi (Astellas Pharma Inc.)
- Keiji Miyata (Astellas Pharma Inc.)
- Seitaro Mutoh (Astellas Pharma Inc.)
- Shigeyuki Yokoyama (RIKEN)
Research Director
Akihiko Yoshimura (Professor, Faculty of Medicine, Keio University)
Year Started: 2009
Research Director
Hisashi Arase (Professor, Osaka University)
- Katsumi Maenaka (Professor, Hokkaido University)
Research Director
Taku Okazaki (Professor, Tokushima University)
Research Director
Hajime Karasuyama (Professor, Tokyo Medical and Dental University)
- Yoshiyuki Minegishi (Professor, Tokushima University)
Research Director
Tatsuo Kinashi (Professor, Institute of Biomedical Sciｅnce, Kansai Medical University)
- Koko Katagiri (Professor, Kitasato University)
Research Director
Tomohiro Kurosaki (Osaka University)
- Koichi Furukawa (Snior Research Professor, College of Life and Health Sciences, Chubu University)
