[The Power of Life] Elucidating the Power of Life through Innovative Measurement and Analysis Techniques

Strategic Objective

Measuring resilience of life - Discovery and exploration of unknown biological response mechanisms

Research Supervisor

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Noboru Mizushima(Professor, Graduate School and Faculty of Medicine, The University of Tokyo)

Overview

 Based on the Strategic Objective Measuring ‘resilience of life’ — Discovery and exploration of unknown biological response mechanisms, the goal of this research area is to elucidate the power of life through a needs-oriented, cross-disciplinary approach that utilizes various measurement parameters. We also aim to develop innovative measurement and analysis techniques to visualize and characterize the power of life, and to elucidate it utilizing the techniques developed.

 In this research area, the concept of the power of life encompasses the fundamental properties of life, including the ability to change dynamically while maintaining a certain identity (dynamism), the ability to withstand harsh environments (robustness), and the ability to constrain fluctuations caused by external stimuli and internal factors (homeostasis). However, the power of life is not limited to these features, and researchers participating in this research area will pursue their own concept of the power of life and seek to elucidate and understand it. The term the power of life includes both the power that life produces and the power that produces life.

 To elucidate the power of life, we will develop innovative measurement and analysis techniques to meet the demands of life sciences by organizing cross-disciplinary teams among researchers. In addition, we aim to reveal the unexplained elements of the power of life by overlaying various parameters, such as measurements over a wide range of temporal and spatial scales of life, and measurements across these scales.

 We hope that this research area will create a new view of life through the development of innovative measurement and analysis techniques that meet the demands of life sciences and the elucidation of previously unknown or neglected elements of the power of life.

Research Area Advisors

Kohjiro Ueki Director, Diabetes Research Center, National Center for Global Health and Medicine
Yasuteru Urano Professor, Graduate School of Pharmaceutical Sciences & Graduate School of Medicine, The University of Tokyo
Jun Ohta Executive Director/Vice President, Nara Institute of Science and Technology
Mitsuo Kawato Director, Brain Information Communication Research Laboratory Group, Advanced Telecommunications Research Institute International
Masatsugu Toyota Professor, Graduate School of Science and Engineering, Saitama University
Takeharu Nagai Vice Director/Professor, SANKEN, Osaka University
Keiko Nakayama Professor, Graduate School of Medicine, Tohoku University / Institute of Research, Institute of Science Tokyo
Tohru Natsume Prime Senior Researcher, Cellular and Molecular Biotechnology Research Institute, The National Institute of Advanced Industrial Science and Technology
Yoshie Harada Professor, Institute for Protein Research, Osaka University
Makoto Higuchi Department Head, Advanced Neuroimaging Center,Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology

Research Projects

  1. Year Started : 2024

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