[Takeharu Nagai] Superresolution of “physiological functions” and diagnostics of activity architecture in live cells


Research Director

Takeharu Nagai

Takeharu Nagai

Institute of Scientific and Industrial Research, Osaka University
Professor
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Outline

Various cellular compartments with nanometer scale play as platforms for a lot of physiological events such as ion flow, heat generation, enzymatic reactions, and signal transduction. Although superresolution technique allows us to visualize such cellular compartment structure with nanometer resolution, it cannot apply to imaging of cellular functions. To overcome this problem, we aim to create nanoscopic techniques to observe hitherto-invisible activity architecture in the cellular compartments and a data mining technique to efficiently process the massive extremely-high-dimension data of super-resolved images so as to find information that characterizes the states of cells.

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