Outline
This research field focuses on the construction of novel, fundamental measurement and analysis techniques for interpreting as yet unexplained life phenomena which are the driving force behind the development of life science technologies. Specifically, emphasis is placed on analysis techniques which reveal the true nature of the mechanism of interaction between organic molecules, which govern life phenomena, as well as techniques that can be used for in situ observations of biological entities or organic molecules inside cells, analysis techniques applicable at the level of individual cells, and novel measurement and analysis techniques applicable on any scale ranging from individual entities to entire ecosystems.Furthermore, novel techniques are sought for measuring and analyzing the influence exerted on biological entities by materials whose abundance in the environmental probes is extremely low.In addition, even for techniques based on existing fundamental principles, this field includes research which is expected to yield breakthrough research and life science technologies that can drastically improve the speed, sensitivity and resolution of measurements and analyses or can break the limitations associated with these factors. Such breakthroughs are also expected in the pursuit of new principles, and in the research and material science techniques related to the discovery and clarification of new phenomena.
Strategic Sector
Creation of Basic Technology for the Realization of Leading Edge Measuring and Analytical Equipment through the Development of New Techniques, etc
Research Projects
Research Director | Affiliation | Research Project |
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Yuji C. Sasaki | Professor, The University of Tokyo | Observations of Biomolecular Structural Recognition Process from Highly Accurate Individual Single Molecular Movies |
Yoshikazu Nakayama | Professor, Osaka University | Measurement of Biological-single-molecule Dynamics by Carbon-nanotube Devices |
Kuniaki Nagayama | Professor, National Institutes of Natural Sciences (NINS) | Development of ns-nm Resolution Electron- Photon Hybrid Microscope |
Hideo Higuchi | Professor, The University of Tokyo | In Vivo Nano-imaging of Movement of Molecules in Mice |
Atsuo Miyazawa | Professor, University of Hyogo | Biomolecular Tomography with Molecular Labels in the Cell |
Research Director | Affiliation | Research Project |
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Shigeru Aoyama | General Manager, OMRON Corp. | Investigation on the Enviornment Response of Biomolecule with Hybrid Localized SPR |
Tetsuo Nagano | Professor, The University of Tokyo | Development and Application of Chemical Probes for Dynamic Visualization of Biomolecules |
Yoshikazu Nakamura | Professor, The University of Tokyo | Multi-target Development of RNA-based 'Nanosensors' and 'Modulators' |
Yusuke Mori | Professor, Osaka University | Creation of Perfect Protein Crystals |
Yoshichika Yoshioka | Specially Appointed Professor, Osaka University | The Development of the Noninvasive Quantitative Brain Functional Imaging Technique |
Research Director | Affiliation | Research Project |
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Toshio Ando | Professor, Kanazawa University | Development of High-speed Imaging Apparatus for Studying Nanometer Scale Dynamic Behavior of Protein |
Koji Ikuta | Professor, Nagoya University | New Principle Measurement Tools using Optical-driven Nano Machine |
Masahiro Shirakawa | Professor, Kyoto University | Noninvasive Detection of Biomolecules in Living Organisms by Magnetic Resonance |
Satoshi Takahashi | Professor, Tohoku University | Development of a New Observation Method for the Single Molecule Dynamics of Protein Folding |