論文・成果
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*Gong, H.T., Sakaguchi, Y., Suzuki, T., Yanagisawa, M. and *Aida, T. Near-identical macromolecules spontaneously partition into concentric circles Nature, 636, 92(2024) -
*Suzuki, T., Ogizawa, A., Ishiguro, K. and Nagao, A. Biogenesis and roles of tRNA queuosine modification and its glycosylated derivatives in human health and diseases Cell Chemical Biology, 32, 227(2024) -
Kurata, T., Takegawa, M., Ohira, T., Syroegin, E.A., Atkinson, G.C., Johansson, M.JO, Polikanov, Y.S., Garcia-Pino, A., *Suzuki, T. and *Hauryliuk, V. Toxic Small Alarmone Synthetase FaRel2 inhibits translation by pyrophosphorylating tRNAGly and tRNAThr Science Advances, 10, eadr9624(2024) -
Yamazaki, Y., Ito, T., Nakagawa, S., Sugihira, T., Villaruz, A. E., Ishiguro, K., Salcman, B., Li, S., Takada, S., Inohara, N., Kusuya, Y., Shibata, A., Tamai, M., Aoyama, R., Inoue, K., Murata, S., Matsushita, K., Miyabe, A., Taniguchi, T., Igari, H., Ishiwada, N., Taniguchi, M., Nakada, T., Matsue, H., Fujimoto, M., Hishiki, H., Osone, Y., Hamada, H., Shimojo, N., Suzuki, T., Otto, M., Núñez, G., Takahashi, H., Takaya, A., and *Nakamura, Y. Altered Genomic Methylation Promotes Staphylococcus aureus Persistence in Hospital Environment Nature communications, 15, 9619(2024) -
Akichika, S and Suzuki, T.* Cap-specific m6Am modification: A transcriptional anti-terminator by sequestering PCF11 with implications for neuroblastoma therapy Molecular Cell, 84, 4051(2024) -
Hidetaka S. Oshima, Akiko Ogawa, Fumiya K. Sano, Hiroaki Akasaka, Tomoyoshi Kawakami, Aika Iwama, Hiroyuki H. Okamoto, Chisae Nagiri, Fan-Yan Wei*, Wataru Shihoya*, Osamu Nureki* Structural insights into the agonist selectivity of the adenosine A 3 receptor Nature communications, 15, 9294(2024) -
Maharjan, S., Gamper, H., Yamaki, Y., Henley, R. Y., Li, N-S., Suzuki, T., Suzuki, T., Piccirilli, J. A., Wanunu, M., Seifert, E., Wallace, D. C., and Hou, Y-M. Post-transcriptional methylation of mitochondrial-tRNA differentially contributes to mitochondrial pathology Nature communications, 15, 9008(2024) -
Hirohito Yamazaki, Ryusei Sugawara, Yurito Takayama Development of label-free light-controlled gene expression technologies using mid-IR and terahertz light Frontiers in Bioengineering and Biotechnology, 12, 1324757(2024) -
Matsuura, J., Akichika, S., Wei, F.Y., Suzuki, T., Yamamoto, T., Watanabe, Y., Valášek, L. S., Mukasa, A., *Tomizawa, K., and *Chujo, T. Human DUS1L catalyzes dihydrouridine modification at tRNA positions 16/17, and DUS1L overexpression perturbs translation Communications biology, 7, 1238(2024) -
Miyauchi, K.+, Kimura, S.+, Akiyama, N.+, Inoue, K., Ishiguro, K., Vu, T.S., Srisuknimit, V., Koyama, K., Hayashi, G., Soma, A., Nagao, A., Shirouzu, M., Okamoto, A., *Waldor, M., and *Suzuki, T. A tRNA modification with aminovaleramide facilitates AUA decoding in protein synthesis Nature Chemical Biology, 21, 522(2024) -
Yu, B., Nagae, G., Midorikawa, Y., Tatsuno, K., Dasgupta, B., Aburatani, H., & Ueda, H. m6ATM: a deep learning framework for demystifying the m6A epitranscriptome with Nanopore long-read RNA-seq data Briefings in Bioinformatics, 25, (2024) -
Tsutomu Suzuki Glycosylated tRNA modifications and their physiological functions Glycofurum, 27, A21(2024) -
Hikaru Nozawa, Fritz Nagae, Satoshi Ogihara, Rina Hirano, Hirohito Yamazaki, Ryo Iizuka, Munetaka Akatsu, Tomoya Kujirai, Shoji Takada, Hitoshi Kurumizaka, Sotaro Uemura Nucleosomal DNA unwinding pathway through canonical and non-canonical histone disassembly Communications Biology, 7, 1144(2024) -
Ishikawa K, Miyata D, Hattori S, Tani H, Kuriyama T, Wei FY, Miyakawa T, Nakada K. Accumulation of mitochondrial DNA with a point mutation in tRNALeu(UUR) gene induces brain dysfunction in mice. Pharmacol Res., 208, 107374(2024) -
Tresky R, Miyamoto Y, Nagayoshi Y, Yabuki Y, Araki K, Takahashi Y, Komohara Y, Ge H, Nishiguchi K, Fukuda T, Kaneko H, Maeda N, Matsuura J, Iwasaki S, Sakakida K, Shioda N, Wei FY, Tomizawa K, Chujo T. TRMT10A dysfunction perturbs codon translation of initiator methionine and glutamine and impairs brain functions in mice. Nucleic Acids Res., 52, 9230(2024) -
Ryota Hidese, Takayuki Ohira, Satsuki Sakakibara, Tsutomu Suzuki, Naoki Shigi, Shinsuke Fujiwara Functional redundancy of ubiquitin-like sulfur-carrier proteins facilitates flexible, efficient sulfur utilization in the primordial archaeon Thermococcus kodakarensis Mbio, 15, e00534-24(2024) -
Hirohito Yamazaki, Takuya Mabuchi, Kouta Kaito, Kyosuke Matsuda, Hiromu Kato, Sotaro Uemura Photothermally Heated Asymmetric Thin Nanopores Suggest the Influence of Temperature on the Intermediate Conformational State of Cytochrome c in an Electric Field Nano Letters, 24, 10219(2024) -
Akiyama, N., Ishiguro, K., Yokoyama, T., Miyauchi, K., Nagao, A., Shirouzu, M., and *Suzuki, T. Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine Nature Struct Mol Biol., 31, 817(2024) -
Yang, Y., Nakayama, K., Okada, S., Sato, K., Wada, T., Sakaguchi, Y., Murayama, A., Suzuki, T., Sakurai, M. ICLAMP: A Novel Technique to Explore Adenosine Deamination via Inosine Chemical Labeling and Affinity Molecular Purification FEBS Lett., 598, 1080(2024) -
Liu, J., Yashiro, Y., Sakaguchi, Y., Suzuki, T. and Tomita, K. Substrate specificity of Mycobacterium tuberculosis tRNA terminal nucleotidyltransferase toxin MenT3 Nucleic Acids Res., 52, 5987(2024) -
Lu, W., Terasaka, H., Sakaguchi, Y., Suzuki, T., Suzuki, T. and Suga, H. An anticodon-sensing T-boxzyme generates the elongator nonproteinogenic aminoacyl-tRNA in situ of a custom-made translation system for incorporation Nucleic Acids Res., 52, 3938(2024) -
Ohira, T. and *Suzuki, T Transfer RNA modifications and cellular thermotolerance Molecular Cell, 84, 94(2024)
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