RESEARCH SUMMARY
The long-term goal of the project is to decipher mechanisms underlying the structural and functional establishment and maintenance of the complex, non-linear and multi-scale organization of our body consisting of the network of multiple organs. The project consists of three research groups: Integrative Biodynamic Group, Contextual Biology Group, In vivo Organelle Biology Group.
Integrative Biodynamics Group
We study mechanisms underlying the structural and functional establishment and maintenance of the complex, non-linear and multi-scale organization of our body consisting of the network of multiple organs. We investigate such system at single cell, multi-cell, organ, inter-organ, whole body levels and our ultimate aim is to understand the principle of the structural and functional organization of our body at the systems levels that can integrate the cellular and molecular mechanisms. We extensively utilize state-of-the-art molecular and biological tools with both zebrafish and mouse models, combined with mathematical and computational approaches. We also conduct clinical research to facilitate the applications of our findings and technical innovations to humans with the ultimate goal to develop more efficient and effective diagnostic and therapeutic methods.
Collaborative Research Institution
Nara Medical University