Neuronal individuality providing neural circuit formation and cell assembly

Research Project Outline

The brain contains an enormous number of neurons, which are assembled into functional neural networks and also retain individuality. Clustered protocadherin (cPcdh) molecules are candidates for the molecular codes that provide neuronal individuality and specific neural network formation. In this study, we investigate the molecular mechanisms responsible for generating local neural networks and functional cell assembly in the brain by using molecular tools and manipulations to control the expression and function of cPcdh molecules. We aim to reveal the biological basis of sparse parallel-distributed processing of neural information in the brain.

Research Director
TakeshiYagi
Affiliation
Professor, Osaka University
Research Started
2011
Status
ongoing
Research Area
Elucidation of the Principles of Formation and Function of the Brain Neural Network and Creation of Control Technologies
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