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Research Project Outline
The aim of this study is to reveal how voluntary movement is represented in cortical circuits. We will combine a number of cutting-edge techniques to clarify the activity, distribution, and connections of the cortical neurons that are involved in sequential motor phases. The activities of the cortical neurons will be modulated by using 'optogenetic' tools to clarify the direction of flow of motor information. Our results will provide insights into the principles of circuit operation and the cellular basis for recovery from brain cortical damage.