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Clarification of Dermatological Disease Mechanisms through Collaboration of Physiology and Mathematical Science

Research Project Outline

"Stratum corneum plays an important role as a barrier function, and it is known that its failure relates to various dermatological diseases. We will establish a mathematical model for the dynamics seen in keratinocytes and confirm the validity of the model through physiological experiments. Using the model, we will understand how to realize the barrier function of a skin from the viewpoints of both physiology and mathematical science. Through these approaches, we aim to clarify the cause and treatment of diseases related to the failure of the barrier function."

Research Director
MasaharuNagayama
Affiliation
Professor, Kanazawa University
Research Started
2010
Status
ongoing
Research Area
Alliance for Breakthrough between Mathematics and Sciences (ABMS)
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