Elucidation of the Significance of Phospholipids Molecular Species in Biological Membranes

Research Project Outline

It is well known that phospholipids present in biological membranes consist of various molecular species with different fatty acyl chains. However, the physiological significance of individual phospholipid and the molecular mechanisms of their formation are not fully elucidated. In this project, we utilize C. elegans genetics and mass spectrometry techniques to identify the enzymes for the formation of phospholipids molecular species and to isolate the membrane proteins requiring phospholipids with very long polyunsaturated fatty acids for their functions.

Research Director
Professor, The University of Tokyo
Research Started
Research Area
Basic Technologies for Controlling Cell Functions Based on Metabolic Regulation Mechanism Analysis
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Research Areas Completed
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