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Development of Mass Spectrometry-based Analytical Platform of Small RNAs

Research Project Outline

Recent genetic and biochemical evidence reveals important regulatory roles of diverse types of small RNA and protein complexes in various biological events. In this study, we will develop mass spectrometry-based technologies that offer sensitive and efficient solutions to analysis of the sequence, structure, modification and composition of small RNAs. Final goal of this study is to integrate these technologies with proteomics and allows comprehensive analysis of functional networks of ribonucleoproteome in a cell.

Research Director
ToshiakiIsobe
Affiliation
Professor, Tokyo Metropolitan University
Research Started
2006
Status
ongoing
Research Area
Basic Technologies for Controlling Cell Functions Based on Metabolic Regulation Mechanism Analysis
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