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Mechanisms of Regulation of Cell Functions Maintaining Glucose Homeostasis

Research Project Outline

Glucose metabolism is an essential bioreaction in the maintenance of life in living organisms. Islet of Langerhans in pancreas (pancreatic islet) is the most important sub-organ in the maintenance of glucose homeostasis. Loss of function of pancreatic islets causes severe disorders of glucose homeostasis such as diabetes mellitus. In this project, we aim to develop a basis for novel diagnoses and therapies for metabolic disorders that include diabetes, as well as clarify the pathogenesis of these diseases. We plan comprehensive metabolome analysis of islet cells to clarify the molecular mechanisms of regulation of pancreatic islet functions.

Research Director
Professor, Kobe University
Research Started
Research Area
Basic Technologies for Controlling Cell Functions Based on Metabolic Regulation Mechanism Analysis
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