Research Project Outline
Generating polarities is an essential event during the early phase of embryogenesis. In this study, we will focus on anterioposterior and left-right poralities, and wish to reveal how these polaries are generated in the mouse. Signaling molecules (Nodal and Lefty) that determine these polarities will be visualized in the mouse embryo. By combining experimental data with theoretical modeling, we wish to reveal the principle that controls embryonic patterning.