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Research Project Outline
Small RNAs trigger various forms of sequence-specific gene silencing, which is now collectively referred to as RNA silencing. It is becoming clear that RNA silencing is involved in multiple pathways in eukaryotes, including developmental transition, organogenesis, metabolism, and genome surveillance. Thus, it enables the integration and networking of complex suites of gene activity, thereby elaborating multicellular complexity. Our goal is to elucidate how RNA silencing pathways function in Drosophila and reach a deeper understanding of complexity of biological systems involving RNA silencing mechanisms.