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Identification of Endophenotype in Psychiatric Disorders using Genetically Engineered Mice

Research Project Outline

Elucidating the factors underlying psychiatric illness is hampered by current methods of clinical diagnosis. The identification of biological endophenotypes is essential, but represents a considerable challenge in human subjects. In this project, we first try to identify endophenotypes in genetically-engineered mice showing behaivoral abnormalities related to pscyhiatirc disorders. And then we investigate human subjects, utilizing the knowledge obtained in mice. Our project will reveal molecular and neural mechanisms underlying psychiatric disoreders.

Research Director
TsuyoshiMiyakawa
Affiliation
Professor, Fujita Health University
Research Started
2007
Status
ongoing
Research Area
Creation of a Novel Technology towards Diagnosis and Treatment based on Understanding of Molecular Pathogenesis of Psychiatric and Neurological Disorders
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