Research Project Outline
Mucosa is a major entry site for antigens and its associated lymphoid tissues comprise a unique system of dendritic cells (DC) that maintains immune tolerance. In this research project, we will elucidate the induc-tion mechanisms of DC-mediated mucosal immune tolerance and disorders. Based on the results, we will further aim at the development of DC-based technology for prevention and treatment of mucosal im-mune disorders.