The Generation of High-Quality Human iPS Cells And Their Characterization

Research Project Outline

There are considerable differences between human and mouse iPS cells in the developmental state. Mouse iPS cells are closer to the ground state than human iPS cells. iPS cells derived from other animals (e.g. monkeys and pigs) are similar to human iPS cells in terms of the developmental state. The purpose of this study is to bring human, monkey, and pig iPS cells into the ground state to generate high-quality ones. We will also show what we can do using the high-quality iPS cells (dissociated culture, homologous recombination, animal developmental engineering, etc.).

Related Links

• Laboratory Website: http://www.jichi.ac.jp/saisei/Top_English.html