Molecular mechanisms of transcriptional regulation in cell reprogramming and differentiation

Research Project Outline

This study aims at (I) elucidation of molecular mechanisms of changes in transcriptional programs during cell reprogramming, (II) understanding of transcriptional programs in cell differentiation processes, (III) establishment and molecular analyses of automated programs for transdifferentiation, and (IV) analyses on the action mechanisms of transcription factors and the molecular mechanisms of epigenetic regulation. Thus, this study will provide molecular bases for generation of various tissues and organs from iPS cells.

Research Director
EisukeNishida
Affiliation
Professor, Kyoto University
Research Started
2009
Status
ongoing
Research Area
Fundamental Technologies for Medicine Concerning the Generation and Regulation of Induced Pluripotent Stem (iPS) Cells
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