In vivo directed reprogramming of neural crest cells

Research Project Outline

The iPS technology has opened a way to reprogram differentiated cells into other cell types. Progress of iPS research has mostly been made in vitro system, which requires a long-term cell culture and subsequent cell transplantation into host animals. We aim to establish an in vivo directed reprogramming technology with neural crest cells as a model. Neural crest cells are a population of stem cells that give rise to peripheral nervous system and pigment cells. The principle of technology developed for neural crest cells can also be applied to other cells/tissues, and it will therefore serve as a general basis for advanced regenerative medicine.

Research Director
Professor, Nara Institute of Science and Technology
Research Started
Research Area
Fundamental Technologies for Medicine Concerning the Generation and Regulation of Induced Pluripotent Stem (iPS) Cells
Research Areas by Category
Research Areas Completed
Researcher Index