Development of Multi-quantum Coherent ESR and Elucidation of Macromolecular Structure

Research Project Outline

To elucidate the macromolecular structure, we developed the double-quantum coherent (DQC) ESR system. We succeeded to detect the DQC signal from the bilabeled proteins, and analyzed the distances of 2-6 nm. The further development of a distance distribution analysis system and new-type of resonators allowed elucidating the complex proteins, such as biomembranes proteins. (Research term: 1 Oct. 2004 - 30 Sep. 2007)