GROUPBiochemistry Group

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   Research Director
   / Group Leader

  Tsutomu Suzuki

  Department of Chemistry and Biotechnology, Graduate School of Engineering, the University of Tokyo Professor

  We search for novel RNA modifications from human cells and other organisms, and determine their chemical structures by RNA mass spectrometry. We also identify novel RNA-modifying enzymes and their genes, and study biogenesis and physiological function of the RNA modifications. To map and quantify all the modifications in human tRNAs, we develop a game-changing platform technology using nanopore sequencing of RNA modifications assisted by neural networks and deep learning. We attempt to control cellular processes by artificially manipulating RNA modifications, thereby establishing a technological basis for future drug discovery and therapeutic measures.

Group Members

・Yuriko Sakaguchi (Researcher)
・Kenjyo Miyauchi (Researcher)
・Shin-ichiro Akichika (Researcher)

・Takeo Suzuki (Researcher)
・Asuteka Nagao (Researcher)
・Takayuki Ohira (Researche)
・Kensuke Ishiguro (Researcher)
・Ayaka Murayama (Technician)

・Hangyan Sun (D1 Research Assistant)
・Yao Xiao (D1 Research Assistant)

・Ittoku Kikuchi (D3)
・Keiichi Minowa (D3)
・Mayuko Takakura (D2)
・Vu T. Son (D1)
・Yufeng Mo (D1)
・Ayumi Nishi (D1)
・Koichiro Tsurumi (M2)
・Naho Akiyama (M2)
・Yuka Suzuki (M2)
・Ena Tomoda (M2)
・Mai Maeda (M2)
・Akira Mineo (M2)
・Lei Li (M2)
・Haruka Shioya (M1)
・Ren Nakazaki (M1)
・Ryo Noguchi (M1)
・Taishi Fujio (M1)