Last Update:2013.02.01
SAITOU Totipotent Epigenome > Publications
Publications
2013
- Hayashi, K., and Saitou, M. (2013).
- Stepwise differentiation from naive state pluripotent stem cells to functional primordial germ cells through an epiblast-like state.
- Methods in Molecular Biology, in press
- Yamaji, M., Ueda, J., Hayashi, K., Ohta, H., Yabuta, Y., Kurimoto, K., Nakato, R., Shirahige, K., and Saitou, M. (2013).
- PRDM14 ensures naive pluripotency through dual regulation of signaling and epigenetic pathways in mouse embryonic stem cells.
- Cell Stem Cell, vol12, 368-382 [Cell Stem Cell]
- Kagiwada, S., Kurimoto, K., Hirota, T., Yamaji, M., and Saitou, M. (2013).
- Replication-coupled passive DNA demethylation for the erasure of genome imprints in mice.
- The EMBO Journal (2013), 32, 340 - 353 [The EMBO Journal]
2012
- Hayashi, K., Ogushi, S., Kurimoto, K., Shimamoto, S., Ohta, H., and Saitou, M. (2012).
- Offspring from oocytes derived from in vitro primordial germ cell-like cells in mice.
- Science, 338, 971-975. [Science]
- Mochizuki, K., Tachibana, M., Saitou, M., Tokitake, Y., and Matsui, Y. (2012).
- Implication of DNA demethylation and bivalent histone modification for selective gene regulation in mouse primordial germ cells.
- PloS ONE, 7, e46036. [PloS ONE]
- Saitou, M.., and Yamaji, Masashi. (2012).
- Primordial germ cells in mice.
- CSH Perspectives in Biology, 4. [CSH]
- Saitou, M., Kagiwada, S., and Kurimoto, K. (2012).
- Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells.
- Development, 139, 15-31. [Development]
2011
- Ichiyanagi, K., Li, Y., Watanabe, T., Ichiyanagi, T., and Fukuda, K., Kitayama, J., Yamamoto, Y.,Kuramochi-Miyagawa, S., and Nakano, T., Yabuta, Y., Seki, Y., Saitou, M., and Sasaki, Hiroyuk. . (2011).
- Locus- and domain-dependent control of DNA methylation at mouse B1 retrotransposons during male germ cell development.
- Genome Research, 21, 2058-2066. [PubMed]
- Abe, K., Naruse, C., Kato, T., Nishiuchi, T., Saitou, M., and Asano, M. (2011).
- Loss of hererochromatin protein 1 gamma reduces the number of primordial germ cells via impaired cell-cycle progression in mice
- Biology of Reproduction, 85, 1013-1024. [Biology of Reproduction]
- Lee, J., Ogushi, S., Saitou, M., and Hirano, T. (2011).
- Condensins I and II are essential for construction of bivalent chromosomes in mouse oocytes.
- Molecular Biology of the Cell, 22, 3465-3477. [MBoC]
- Hayashi, K., Ohta, H., Kurimoto, K., Aramaki, S., and Saitou, M. (2011).
- Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells.
- Cell, 146, 519-532. [Cell]
- Hirota, T., Ohta, H., Shigeta, M., Niwa, H., and Saitou, M. (2011)
- Drug-inducible gene recombination by the Dppa3-MER Cre MER transgene in the developmental cycle of the germ cell lineage in mice.
- Biology of Reproduction, 85, 367-377 [Biology of Reproduction]
- Inoue, A., Ogushi, S., Saitou, M., Suzuki, M.G., and Aoki, F. (2011).
- Involvement of murine Nucleoplasmin 2 in the decondensation of sperm chromatin after fertilization.
- Biology of Reproduction, 85, 70-77. [Biology of Reproduction]
- Yabuta, Y., Ohta, H., Abe, T., Kurimoro, K., Chuma, S., and Saitou, M. (2011).
- TDRD5 is required for retrotransposon silencing, chromatoid body assembly and spermiogenesis in mice.
- The Journal of Cell Biology, 192, 781-795. [Kurenai]
- Kurimoto, K., and Saitou, M. (2011).
- A global single-cell cDNA amplification method for quantitative microarray analysis.
- Methods in Molecular Biology, 687, 91-111. [Springer Link]
2010
- Yamagata, K., Ueda, J., Mizutani, E., Saitou, M., and Wakayama, T. (2010).
- Survival and death of epiblast cells during embryonic stem cell derivation revealed by long-term live-cell imaging with an Oct4 reporter system.
- Developmental Biology, 346, 90-101. [PubMed]
- Kurimoto, K., and Saitou, M.(2010)
- Single-cell cDNA microarray profiling of complex biological processes of differentiation.
- Current Opinion in Genetics and Development, 20, 470-477. [SciVerse]
- Ogushi, S., and Saitou, M. (2010).
- The nucleolus in the mouse oocyte is required for the early step of both female and male pronucleus organization.
- Journal of Reproduction and Development, 56, 495-501. [Reproduction and Development]
- Saitou, M., and Yamaji, M. (2010).
- Germ cell specification in mice: Signalling, transcription regulation and epigenetic consequences.
- Reproduction, 139, 931-942. [Reproduction]
- Miyauchi, Y., Ninomiya, K., Miyamoto, H., Sakamoto, A., Iwasaki, R., Hoshi, H., Miyamoto, K., Hao, W., Yoshida, S., Morioka, H., Chiba, K., Kato, S., Tokuhisa, T., Saitou, M., Toyama, Y., Suda, T., and Miyamoto, T. (2010).
- The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.
- Journal of Experimental Medicine, 207, 751-762. [JEM]
- Yamaji, M., Tanaka, T., Shigeta, M., Chuma, S., Saga, Y., and Saitou, M. (2010).
- Functional reconstruction of Nanos3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of Nanos3.
- Reproduction, 139, 381-393. [Reproduction]
2009
- Yamaguchi, S., Kurimoto, K., Yabuta, Y., Sasaki, H., Nakatsuji, N., Saitou, M., and Tada, T. (2009).
- Conditional knockdown of Nanog induces apoptotic cell death in mouse migrating primordial germ cells.
- Development, 136, 4011-4020. [Development]
- Ohta, H., Ohinata, Y., Ikawa, M., Morioka, Y, Sakaide, Y., Saitou, M., Kanagawa, O., and Wakayama, T. (2009).
- Male germline and embryonic stem cell lines from NOD mice: Efficient derivation of GS cells from a nonpermissive strain for ES cell derivation.
- Biology of Reproduction, 81, 1147-1153. [Biology of Reproduction]
- Saitou, M. (2009).
- Germ cell specification in mice.
- Current Opinion in Genetics and Development, 19, 386-395. [SciVerse]
- Ohinata, Y., Ohta, H., Shigeta, M., Yamanaka, K., Wakayama, T., and Saitou, M. (2009).
- A signaling principle for the specification of the germ cell lineage in mice.
- Cell, 137, 571-584. [Cell]
- Saitou, M. (2009).
- Specification of the germ cell lineage in mice.
- Frontiers in Bioscience, 14, 1068-1087. [PubMed]
2008
- Seki, Y., and Saitou, M. (2008).
- Epigenetic reprogramming in primoridial germ cell development.
- Research Signpost, in Genetic and Epigenetic Control of Mammalian Germ Cell Development and Function 2008, 13-35.
- Kurimoto, K., Yamaji, M., Seki, Y., and Saitou, M. (2008)
- Specification of the germ cell lineage in mice: A process orchestrated by the PR-domain proteins, Blimp1 and Prdm14.
- Cell Cycle, 7, 3514-3518. [CellCycle]
- Kawaguchi, A., Ikawa, T., Kasukawa, T., Ueda, H. R., Kurimoto, K., Saitou, M., and Matsuzaki, F. (2008)
- Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis.
- Development, 135, 3113-3124. [Development]
- Ohinata, Y., Sano, M., Shigeta, M., Yamanaka, K., and Saitou, M. (2008).
- A comprehensive, non-invasive visualization of primordial germ cell development in mice by the Blimp1-mVenus and stella-ECFP double transgenic reporter.
- Reproduction, 136, 503-514. [PubMed]
- Yamaji, M., Seki, Y., Kurimoto, K., Yabuta, Y., Yuasa, M., Shigeta, M., Yamanaka, K., Ohinata, Y., and Saitou, M. (2008).
- Critical function of Prdm14 for the establishment of the germ cell lineage in mice.
- Nature Genetics, 40, 1016-1022. [NatureGenetics]
- Kurimoto, K., Yabuta, Y., Ohinata, Y., Shigeta, M., Yamanaka, K., and Saitou, M. (2008).
- Complex genome-wide transcription dynamics orchestrated by Blimp1 for the specification of the germ cell lineage in mice.
- Genes & Development, 22, 1617-1635. [CSH]
- *Ogushi, S., Palmieri, C., Fulka, H., Saitou, M., Miyano, T., and Fulka Jr, J. (2008).
- Maternal nucleolus is essential for early embryonic development in mammals.
- Science, 319, 613-616. *Correspondence [Science]
- Saitou, M., Yabuta, Y., and Kurimoto, K. (2008).
- Single-cell cDNA high-density oligonucleotide microarray analysis: Detection of individual cell types and properties in complex biological processes.
- Reprod. Biomed. Online, 16, 26-40. [Reprod.Bilmed]
2007
- Seki, Y., Yamaji, M., Yabuta, Y., Sano, M., Shigeta, M., Matsui, Y., Saga, Y., Tachibana, M., Shinkai, Y., and Saitou, M. (2007).
- Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice.
- Development, 134, 2627-2638. [Development]
- Kurimoto, K., Yabuta, Y., Ohinata, Y., and Saitou, M. (2007).
- Global single-cell cDNA amplification to provide a template for representative high-density oligonucleotide microarray analysis.
- Nature Protocols, 2, 739-752. [NatureProtocols]
2006
- Horsley, V., O’Carroll, D., Tooze, R., Ohinata, Y., Saitou, M., Obukhanych, T., Nussenzweig, M., Tarakhovsky, A., and Fuchs, E. (2006).
- Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland.
- Cell, 126, 587-609. [Cell]
- Yabuta, Y., Kurimoto, K., Ohinata, Y., Seki, Y., and Saitou, M. (2006).
- Gene expression dynamics during germline specification in mice identified by quantitative single-cell gene expression profiling.
- Biology of Reproduction, 75, 705-716. [Biology of Reproduction]
- Ohinata, Y., Seki, Y., Payer, B., O’Carroll, D., Surani, M. A., and Saitou, M. (2006).
- Germline recruitment in mice: A genetic program for epigenetic reprogramming.
- Ernst Schering Research Foundation Workshop 60, 143-174. [PubMed]
- Kurimoto, K., Yabuta, Y., Ohinata, Y., Ono, Y., Uno, D. K., Yamada, R. G., Ueda, H. R., and Saitou, M. (2006).
- An improved single-cell cDNA amplification method for efficient high-density oligonucleotide microarray analysis.
- Nuc. Acids Res., 34, e42. [Nuc.AcidsRs]
- Payer, B., Chuva de Sousa Lopes, S.M., Barton, S.C., Lee, C., Saitou, M., and Surani, M.A. (2006)
- Generation of stella-GFP transgenic mice, a novel tool to study germ cell development.
- Genesis, 44, 75-83. [PubMed]
2005
- *Saitou, M., Payer, B., O’Carroll, D., Ohinata, Y., and *Surani, M.A. (2005).
- Blimp1 and the emergence of the germ line during development in the mouse.
- Cell Cycle, 4, 1736-1740. * Co-correspondence [CellCycle]
- Western, P., Maldonado-Saldivia, J., van den Bergen, J., Hajkova, P., Saitou, M., Barton, S., and Surani, M.A. (2005).
- Analysis of Esg1 expression in pluripotent cells and the germline reveals similarities with Oct4 and Sox2, and differences between human pluripotent cell lines.
- Stem Cells, 23, 1436-1442 [PubMed]
- Ohinata, Y., Payer, B., O’Carroll, D., Ancelin, K., Ono, Y., Sano, M., Barton, S. C., Obukhanych, T., Nussenzweig, M., Tarakhovsky, A., *Saitou, M., and *Surani, M.A. (2005).
- Blimp1 is a critical determinant of the germ cell lineage in mice.
- Nature, 436, 207-213.* Co-correspondence [PubMed]
- Schulzke, J. D., Gitter, A. H., Mankertz, J., Spiegel, S., Seidler, U., Amasheh, S., Saitou, M., Tsukita, S., and Fromm, M. (2005).
- Epithelial transport and barrier function in occludin-deficient mice.
- Biochim. Biophys. Acta., 1669, 34-42. [PubMed]
- Seki, Y., Hayashi, K., Itoh, K., Mizugaki, M., Saitou, M., and Matsui, Y. (2005).
- Extensive and orderly reprogramming of genome-wide chromatin modifications associated with specification and early development of germ cells in mice.
- Dev. Biol. 278, 440-458. [PubMed]
2004
- Surani, M. A., Ancelin, K., Hajkova, P., Lange, U. C., Payer, B., Western, P., and Saitou, M. (2004).
- Mechanism of mouse germ cell specification: A genetic program regulating epigenetic reprogramming.
- Cold Spring Harbor Symposia on Quantitative Biology, Vol. LXIX., 69, 1-10 [CSH]
2003
- Payer, B., Saitou, M., Barton, S. C., Thresher, R., Dixon, J. P. C., Zahn, D., Colledge, W. H., Carlton, M. B. L., Nakano, T., and Surani, M.A. (2003).
- Stella is a maternal effect gene required for normal early development in mice.
- Curr. Biol. 13, 2110-2117. [Curr.Biol.]
- Saitou, M., Payer, B., Lange, U. C., Erhardt, S., Barton, S. C., and Surani, M.A. (2003)
- Specification of germ cell fate in mice.
- Phil. Trans. Roy. Soc. 358, 1363-1370. [Phil.Trans.Roy.Soc]
- Lange, U. C., Saitou, M., Western, P., Barton, S. C., and Surani, M.A. (2003).
- The Fragilis interferon-inducible gene family of transmembrane proteins is associated with germ cell specification in mice.
- BMC Dev. Biol. 3: Issue 1, 2003. [BMC Dev]
2002
- Saitou, M., Barton, S. C., and Surani, M.A. (2002)
- A molecular programme for the specification of germ cell fate in mice.
- Nature, 418, 293-300. [PubMed]